Siplizumab

From Wikipedia, the free encyclopedia

Siplizumab?
Therapeutic monoclonal antibody
Source Human
Target  ?
Identifiers
CAS number  ?
ATC code  ?
PubChem  ?
Chemical data
Formula  ?
Mol. mass  ?
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Siplizumab (MEDI-507) is a novel MAb with a human IgG1, kappa directed to CD2. The agent has shown potent immunomodulatory effects, selectively suppressing the function of T and NK cells, and is currently being tested as a possible treatment for psoriasis and in the prevention of graft-versus-host disease.[1]


[edit] References

  1. ^ Home - ClinicalTrials.gov