Talk:Silent mutation
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This is an interesting article addressing why silent mutations might not be so silent. [[1]]
If there are parrallel codes in genomic sequences then altering one base pair, while not changing the actual amino acid, might impact other lines of coded information; possibly information pertaining to gene regulation, splicing of pre-mRNA. The more we learn about DNA the more amazing it becomes. --jorgekluney
Hello author of article, You might want to link some of the studies that have been finding dual-coding genes. Talk about exciting! Further research showing that there might be alternate reading-frames in the same genetic segment (overlapping genes *in the same segment* that code for multiple proteins-wow). --jorgekluney
On the other hand, the degree of evolutionary sequence conservation is higher for proteins than for the DNA encoding them, indicating that many or most silent mutations within reading frames are, in fact, silent.
