Talk:Shine-Dalgarno sequence

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just a really badly written article at the moment, we'll see if we can find some sources as a start. Active contributor 01:09, 22 March 2007 (UTC)

Systematic research have shown that in E.coli SD sequence of more than 8 nucleotides can even inhibit translation.

[edit] not all bacteria

The Shine-Dalgarno sequence isn't for all bacteria, it is specific to E. Coli (or possibly other gram negative bacteria?), others would have other named sequences, or the generic term, 'ribosomal binding site'.

[edit] Suggestion

It wouldn't hurt to specify that it's only present in bacteria, and not in eukaryotes, somewhere in the article.

I think this statement is confusing: "When the Shine-Dalgarno sequence and the anti-Shine-Dalgarno sequence pair, the translation initiation factors IF2-GTP, IF1, IF3, as well as the initiator tRNA fMet-tRNA(fMET) are recruited to the ribosome." There isn't any specification as to whether the SD sequence is helping to recruit the IF's and initiator tRNA, or if the IF's and tRNA jut happen to go to the ribosome while the SD and anti-SD sequence are interacting. Since the word "recruit" is used, it seems that the SD is an active participant in bringing those factors and the tRNA to the ribosome. I do not myself know the answer to this question, but I think it would be very helpful if someone with some expertise could clarify the ambiguity. —Preceding unsigned comment added by 131.96.91.26 (talk) 15:31, 6 November 2007 (UTC)

[edit] BOX

maybe you should also add that it's also called shine dagarno BOX .. to make finding it in search easier? —Preceding unsigned comment added by 65.94.6.46 (talk) 21:53, 10 December 2007 (UTC)