SH3BP5

From Wikipedia, the free encyclopedia

SH3-domain binding protein 5 (BTK-associated)

Identifiers

External IDs

OMIM: 605612 MGI: 1344391 HomoloGene: 23450

Gene ontology
Molecular Function:	• protein kinase inhibitor activity • SH3/SH2 adaptor activity • protein binding
Cellular Component:	• cytoplasm • mitochondrion
Biological Process:	• intracellular signaling cascade

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_001018009 (mRNA)
NP_001018009 (protein)

NM_011894 (mRNA)
NP_036024 (protein)

Location

Chr 3: 15.27 - 15.35 Mb

Chr 14: 30.19 - 30.27 Mb

Pubmed search

[1]

[2]

SH3-domain binding protein 5 (BTK-associated), also known as SH3BP5, is a human gene.^[1]

[edit] References

^ Entrez Gene: SH3BP5 SH3-domain binding protein 5 (BTK-associated).

[edit] Further reading

Matsushita M, Yamadori T, Kato S, et al. (1998). "Identification and characterization of a novel SH3-domain binding protein, Sab, which preferentially associates with Bruton's tyrosine kinase (BtK).". Biochem. Biophys. Res. Commun. 245 (2): 337–43. doi:10.1006/bbrc.1998.8420. PMID 9571151.
Yamadori T, Baba Y, Matsushita M, et al. (1999). "Bruton's tyrosine kinase activity is negatively regulated by Sab, the Btk-SH3 domain-binding protein.". Proc. Natl. Acad. Sci. U.S.A. 96 (11): 6341–6. PMID 10339589.
Baba Y, Matsushita M, Matsuda Y, et al. (2000). "Assignment of SH3BP5/Sh3bp5 encoding sab, an SH3 domain-binding protein which preferentially associates with Bruton's tyrosine kinase, to human chromosome 1q43 and mouse chromosome 14B by in situ hybridization.". Cytogenet. Cell Genet. 87 (3-4): 221–2. PMID 10702676.
Wiltshire C, Matsushita M, Tsukada S, et al. (2002). "A new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondria.". Biochem. J. 367 (Pt 3): 577–85. doi:10.1042/BJ20020553. PMID 12167088.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
Court NW, Kuo I, Quigley O, Bogoyevitch MA (2004). "Phosphorylation of the mitochondrial protein Sab by stress-activated protein kinase 3.". Biochem. Biophys. Res. Commun. 319 (1): 130–7. doi:10.1016/j.bbrc.2004.04.148. PMID 15158451.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Wiltshire C, Gillespie DA, May GH (2005). "Sab (SH3BP5), a novel mitochondria-localized JNK-interacting protein.". Biochem. Soc. Trans. 32 (Pt 6): 1075–7. doi:10.1042/BST0321075. PMID 15506969.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.