SGOL1

From Wikipedia, the free encyclopedia

Shugoshin-like 1 (S. pombe)

Identifiers

SGOL1; NY-BR-85; Sgo1

External IDs

OMIM: 609168 MGI: 1919665 HomoloGene: 23642

Gene ontology
Molecular Function:	• protein binding
Cellular Component:	• chromosome, pericentric region • nucleus
Biological Process:	• cell cycle • mitosis • meiotic chromosome segregation • cell division

Orthologs

Human

Mouse

Refseq

NM_001012409 (mRNA)
NP_001012409 (protein)

NM_028232 (mRNA)
NP_082508 (protein)

Location

Chr 3: 20.18 - 20.2 Mb

Chr 17: 53.14 - 53.15 Mb

Pubmed search

[1]

[2]

Shugoshin-like 1 (S. pombe), also known as SGOL1, is a human gene.^[1]

[edit] References

^ Entrez Gene: SGOL1 shugoshin-like 1 (S. pombe).

[edit] Further reading

Wang X, Dai W (2005). "Shugoshin, a guardian for sister chromatid segregation.". Exp. Cell Res. 310 (1): 1-9. doi:10.1016/j.yexcr.2005.07.018. PMID 16112668.
Fu G, Ding X, Yuan K, et al. (2007). "Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis.". Cell Res. 17 (7): 608-18. doi:10.1038/cr.2007.55. PMID 17621308.
Pouwels J, Kukkonen AM, Lan W, et al. (2007). "Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1.". Cell Cycle 6 (13): 1579-85. PMID 17617734.
Fu G, Hua S, Ward T, et al. (2007). "D-box is required for the degradation of human Shugoshin and chromosome alignment.". Biochem. Biophys. Res. Commun. 357 (3): 672-8. doi:10.1016/j.bbrc.2007.03.204. PMID 17448445.
Yang Y, Wang X, Dai W (2006). "Human Sgo1 is an excellent target for induction of apoptosis of transformed cells.". Cell Cycle 5 (8): 896-901. PMID 16628005.
Tang Z, Shu H, Qi W, et al. (2006). "PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation.". Dev. Cell 10 (5): 575-85. doi:10.1016/j.devcel.2006.03.010. PMID 16580887.
Kitajima TS, Sakuno T, Ishiguro K, et al. (2006). "Shugoshin collaborates with protein phosphatase 2A to protect cohesin.". Nature 441 (7089): 46-52. doi:10.1038/nature04663. PMID 16541025.
McGuinness BE, Hirota T, Kudo NR, et al. (2006). "Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells.". PLoS Biol. 3 (3): e86. doi:10.1371/journal.pbio.0030086. PMID 15737064.
Kitajima TS, Hauf S, Ohsugi M, et al. (2005). "Human Bub1 defines the persistent cohesion site along the mitotic chromosome by affecting Shugoshin localization.". Curr. Biol. 15 (4): 353-9. doi:10.1016/j.cub.2004.12.044. PMID 15723797.
Tang Z, Sun Y, Harley SE, et al. (2005). "Human Bub1 protects centromeric sister-chromatid cohesion through Shugoshin during mitosis.". Proc. Natl. Acad. Sci. U.S.A. 101 (52): 18012-7. doi:10.1073/pnas.0408600102. PMID 15604152.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Scanlan MJ, Gout I, Gordon CM, et al. (2003). "Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression.". Cancer Immun. 1: 4. PMID 12747765.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.