SFRS5

From Wikipedia, the free encyclopedia

Splicing factor, arginine/serine-rich 5

Identifiers

SFRS5; HRS; SRP40

External IDs

Gene ontology
Molecular Function:	• nucleotide binding • nucleic acid binding • RNA binding • protein binding
Cellular Component:	• nucleus
Biological Process:	• mRNA splice site selection • mRNA processing • RNA splicing

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_001039465 (mRNA)
NP_001034554 (protein)

XM_886902 (mRNA)
XP_891995 (protein)

Location

Chr 14: 69.26 - 69.31 Mb

n/a

Pubmed search

[1]

[2]

Splicing factor, arginine/serine-rich 5, also known as SFRS5, is a human gene.^[1]

[edit] References

^ Entrez Gene: SFRS5 splicing factor, arginine/serine-rich 5.

[edit] Further reading

Zahler AM, Lane WS, Stolk JA, Roth MB (1992). "SR proteins: a conserved family of pre-mRNA splicing factors.". Genes Dev. 6 (5): 837–47. PMID 1577277.
Screaton GR, Cáceres JF, Mayeda A, et al. (1995). "Identification and characterization of three members of the human SR family of pre-mRNA splicing factors.". EMBO J. 14 (17): 4336–49. PMID 7556075.
Diamond RH, Du K, Lee VM, et al. (1993). "Novel delayed-early and highly insulin-induced growth response genes. Identification of HRS, a potential regulator of alternative pre-mRNA splicing.". J. Biol. Chem. 268 (20): 15185–92. PMID 7686911.
Gui JF, Lane WS, Fu XD (1994). "A serine kinase regulates intracellular localization of splicing factors in the cell cycle.". Nature 369 (6482): 678–82. doi:10.1038/369678a0. PMID 8208298.
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. PMID 9110174.
Snow BE, Heng HH, Shi XM, et al. (1997). "Expression analysis and chromosomal assignment of the human SFRS5/SRp40 gene.". Genomics 43 (2): 165–70. doi:10.1006/geno.1997.4794. PMID 9244433.
Du K, Taub R (1998). "Alternative splicing and structure of the human and mouse SFRS5/HRS/SRp40 genes.". Gene 204 (1-2): 243–9. PMID 9434190.
Blencowe BJ, Issner R, Nickerson JA, Sharp PA (1998). "A coactivator of pre-mRNA splicing.". Genes Dev. 12 (7): 996–1009. PMID 9531537.
Papoutsopoulou S, Nikolakaki E, Chalepakis G, et al. (1999). "SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1.". Nucleic Acids Res. 27 (14): 2972–80. PMID 10390541.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Guil S, Gattoni R, Carrascal M, et al. (2003). "Roles of hnRNP A1, SR proteins, and p68 helicase in c-H-ras alternative splicing regulation.". Mol. Cell. Biol. 23 (8): 2927–41. PMID 12665590.
Liu L, Amy V, Liu G, McKeehan WL (2003). "Novel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis, interaction cloning in yeast, and colocalization in cultured cells.". In Vitro Cell. Dev. Biol. Anim. 38 (10): 582–94. PMID 12762840.
Li J, Hawkins IC, Harvey CD, et al. (2003). "Regulation of alternative splicing by SRrp86 and its interacting proteins.". Mol. Cell. Biol. 23 (21): 7437–47. PMID 14559993.
de Graaf K, Hekerman P, Spelten O, et al. (2004). "Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors.". J. Biol. Chem. 279 (6): 4612–24. doi:10.1074/jbc.M310794200. PMID 14623875.
Hillman RT, Green RE, Brenner SE (2005). "An unappreciated role for RNA surveillance.". Genome Biol. 5 (2): R8. doi:10.1186/gb-2004-5-2-r8. PMID 14759258.
Ropers D, Ayadi L, Gattoni R, et al. (2004). "Differential effects of the SR proteins 9G8, SC35, ASF/SF2, and SRp40 on the utilization of the A1 to A5 splicing sites of HIV-1 RNA.". J. Biol. Chem. 279 (29): 29963–73. doi:10.1074/jbc.M404452200. PMID 15123677.
Caputi M, Freund M, Kammler S, et al. (2004). "A bidirectional SF2/ASF- and SRp40-dependent splicing enhancer regulates human immunodeficiency virus type 1 rev, env, vpu, and nef gene expression.". J. Virol. 78 (12): 6517–26. doi:10.1128/JVI.78.12.6517-6526.2004. PMID 15163745.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.