SFRS2

From Wikipedia, the free encyclopedia

Splicing factor, arginine/serine-rich 2

Identifiers

SFRS2; PR264; SC-35; SC35; SFRS2A; SRp30b

External IDs

OMIM: 600813 MGI: 98284 HomoloGene: 37721

Gene ontology
Molecular Function:	• nucleotide binding • nucleic acid binding • transcription corepressor activity • RNA binding • protein binding
Cellular Component:	• nucleus • PML body
Biological Process:	• mRNA processing • RNA splicing

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_003016 (mRNA)
NP_003007 (protein)

NM_011358 (mRNA)
NP_035488 (protein)

Location

Chr 17: 72.24 - 72.24 Mb

Chr 11: 116.67 - 116.67 Mb

Pubmed search

[1]

[2]

Splicing factor, arginine/serine-rich 2, also known as SFRS2, is a human gene.^[1]

[edit] References

^ Entrez Gene: SFRS2 splicing factor, arginine/serine-rich 2.

[edit] Further reading

Fu XD, Maniatis T (1992). "Isolation of a complementary DNA that encodes the mammalian splicing factor SC35.". Science 256 (5056): 535–8. PMID 1373910.
Sureau A, Soret J, Vellard M, et al. (1993). "The PR264/c-myb connection: expression of a splicing factor modulated by a nuclear protooncogene.". Proc. Natl. Acad. Sci. U.S.A. 89 (24): 11683–7. PMID 1465383.
Vellard M, Sureau A, Soret J, et al. (1992). "A potential splicing factor is encoded by the opposite strand of the trans-spliced c-myb exon.". Proc. Natl. Acad. Sci. U.S.A. 89 (7): 2511–5. PMID 1557353.
Zahler AM, Lane WS, Stolk JA, Roth MB (1992). "SR proteins: a conserved family of pre-mRNA splicing factors.". Genes Dev. 6 (5): 837–47. PMID 1577277.
DuBridge RB, Tang P, Hsia HC, et al. (1987). "Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system.". Mol. Cell. Biol. 7 (1): 379–87. PMID 3031469.
Tacke R, Manley JL (1995). "The human splicing factors ASF/SF2 and SC35 possess distinct, functionally significant RNA binding specificities.". EMBO J. 14 (14): 3540–51. PMID 7543047.
Luznik L, Martone ME, Kraus G, et al. (1995). "Localization of human immunodeficiency virus Rev in transfected and virus-infected cells.". AIDS Res. Hum. Retroviruses 11 (7): 795–804. PMID 7546906.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Kohtz JD, Jamison SF, Will CL, et al. (1994). "Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors.". Nature 368 (6467): 119–24. doi:10.1038/368119a0. PMID 8139654.
Wu JY, Maniatis T (1994). "Specific interactions between proteins implicated in splice site selection and regulated alternative splicing.". Cell 75 (6): 1061–70. PMID 8261509.
Sureau A, Perbal B (1994). "Several mRNAs with variable 3' untranslated regions and different stability encode the human PR264/SC35 splicing factor.". Proc. Natl. Acad. Sci. U.S.A. 91 (3): 932–6. PMID 8302870.
Fu XD (1993). "Specific commitment of different pre-mRNAs to splicing by single SR proteins.". Nature 365 (6441): 82–5. doi:10.1038/365082a0. PMID 8361546.
Bermingham JR, Arden KC, Naumova AK, et al. (1996). "Chromosomal localization of mouse and human genes encoding the splicing factors ASF/SF2 (SFRS1) and SC-35 (SFRS2).". Genomics 29 (1): 70–9. doi:10.1006/geno.1995.1216. PMID 8530103.
Zhang WJ, Wu JY (1996). "Functional properties of p54, a novel SR protein active in constitutive and alternative splicing.". Mol. Cell. Biol. 16 (10): 5400–8. PMID 8816452.
Tronchère H, Wang J, Fu XD (1997). "A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA.". Nature 388 (6640): 397–400. doi:10.1038/41137. PMID 9237760.
Sureau A, Soret J, Guyon C, et al. (1998). "Characterization of multiple alternative RNAs resulting from antisense transcription of the PR264/SC35 splicing factor gene.". Nucleic Acids Res. 25 (22): 4513–22. PMID 9358160.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Zhang WJ, Wu JY (1998). "Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing.". Mol. Cell. Biol. 18 (2): 676–84. PMID 9447963.
Imai Y, Matsuo N, Ogawa S, et al. (1998). "Cloning of a gene, YT521, for a novel RNA splicing-related protein induced by hypoxia/reoxygenation.". Brain Res. Mol. Brain Res. 53 (1-2): 33–40. PMID 9473574.
Parfenov VN, Davis DS, Pochukalina GN, et al. (1998). "Dynamics of distribution of splicing components relative to the transcriptional state of human oocytes from antral follicles.". J. Cell. Biochem. 69 (1): 72–80. PMID 9513048.