SFRS2IP

From Wikipedia, the free encyclopedia

Splicing factor, arginine/serine-rich 2, interacting protein

Identifiers

SFRS2IP; SIP1; CASP11; SRRP129

External IDs

OMIM: 603668 MGI: 1919443 HomoloGene: 37957

Gene ontology
Molecular Function:	• protein binding • RNA splicing factor activity, transesterification mechanism
Cellular Component:	• nucleus • DNA-directed RNA polymerase II, core complex
Biological Process:	• spliceosome assembly • mRNA processing • RNA splicing

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_004719 (mRNA)
NP_004710 (protein)

NM_028148 (mRNA)
NP_082424 (protein)

Location

Chr 12: 44.6 - 44.67 Mb

n/a

Pubmed search

[1]

[2]

Splicing factor, arginine/serine-rich 2, interacting protein, also known as SFRS2IP, is a human gene.^[1]

[edit] References

^ Entrez Gene: SFRS2IP splicing factor, arginine/serine-rich 2, interacting protein.

[edit] Further reading

Gui JF, Lane WS, Fu XD (1994). "A serine kinase regulates intracellular localization of splicing factors in the cell cycle.". Nature 369 (6482): 678–82. doi:10.1038/369678a0. PMID 8208298.
Tanner S, Stagljar I, Georgiev O, et al. (1997). "A novel SR-related protein specifically interacts with the carboxy-terminal domain (CTD) of RNA polymerase II through a conserved interaction domain.". Biol. Chem. 378 (6): 565–71. PMID 9224939.
Zhang WJ, Wu JY (1998). "Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing.". Mol. Cell. Biol. 18 (2): 676–84. PMID 9447963.
van de Craen M, de Jonghe C, van den Brande I, et al. (1999). "Identification of caspases that cleave presenilin-1 and presenilin-2. Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases.". FEBS Lett. 445 (1): 149–54. PMID 10069390.
Scanlan MJ, Gordan JD, Williamson B, et al. (1999). "Antigens recognized by autologous antibody in patients with renal-cell carcinoma.". Int. J. Cancer 83 (4): 456–64. PMID 10508479.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.