SERTAD1

From Wikipedia, the free encyclopedia

SERTA domain containing 1

Identifiers

SERTAD1; SEI1; TRIP-Br1

External IDs

MGI: 1913438 HomoloGene: 8365

Gene ontology
Molecular Function:	• protein binding • transcription activator activity
Biological Process:	• regulation of cyclin-dependent protein kinase activity • transcription • regulation of transcription, DNA-dependent • positive regulation of cell proliferation • positive regulation of transcription

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_013376 (mRNA)
NP_037508 (protein)

NM_018820 (mRNA)
NP_061290 (protein)

Location

Chr 19: 45.62 - 45.62 Mb

Chr 7: 27.2 - 27.2 Mb

Pubmed search

[1]

[2]

SERTA domain containing 1, also known as SERTAD1, is a human gene.^[1]

[edit] References

^ Entrez Gene: SERTAD1 SERTA domain containing 1.

[edit] Further reading

Besley GT, Broadhead DM, Lawlor E (1984). "Acid esterase deficiency: comparison of biochemical findings in infantile and adult forms.". J. Inherit. Metab. Dis. 7 Suppl 2: 155–6. PMID 6434876.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Sugimoto M, Nakamura T, Ohtani N, et al. (2000). "Regulation of CDK4 activity by a novel CDK4-binding protein, p34(SEI-1).". Genes Dev. 13 (22): 3027–33. PMID 10580009.
Hsu SI, Yang CM, Sim KG, et al. (2001). "TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1.". EMBO J. 20 (9): 2273–85. doi:10.1093/emboj/20.9.2273. PMID 11331592.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Hirose T, Fujii R, Nakamura H, et al. (2004). "Regulation of CREB-mediated transcription by association of CDK4 binding protein p34SEI-1 with CBP.". Int. J. Mol. Med. 11 (6): 705–12. PMID 12736710.
Gupta S, Takhar PP, Degenkolbe R, et al. (2004). "The human papillomavirus type 11 and 16 E6 proteins modulate the cell-cycle regulator and transcription cofactor TRIP-Br1.". Virology 317 (1): 155–64. PMID 14675634.
Li J, Melvin WS, Tsai MD, Muscarella P (2004). "The nuclear protein p34SEI-1 regulates the kinase activity of cyclin-dependent kinase 4 in a concentration-dependent manner.". Biochemistry 43 (14): 4394–9. doi:10.1021/bi035601s. PMID 15065884.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Li J, Muscarella P, Joo SH, et al. (2006). "Dissection of CDK4-binding and transactivation activities of p34(SEI-1) and comparison between functions of p34(SEI-1) and p16(INK4A).". Biochemistry 44 (40): 13246–56. doi:10.1021/bi0504658. PMID 16201750.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.