Senile systemic amyloidosis

From Wikipedia, the free encyclopedia

Senile systemic amyloidosis
Classification and external resources
ICD-9 277.3
OMIM 176300
eMedicine med/3365 

Senile systemic amyloidosis is a form of amyloidosis associated with transthyretin.[1]

It is estimated to affect a quarter of the population over 85 years of age.[2]

[edit] References

  1. ^ Westermark P, Sletten K, Johansson B, Cornwell GG (April 1990). "Fibril in senile systemic amyloidosis is derived from normal transthyretin". Proc. Natl. Acad. Sci. U.S.A. 87 (7): 2843–5. PMID 2320592. PMC:53787. 
  2. ^ Tanskanen M, Peuralinna T, Polvikoski T, et al (2008). "Senile systemic amyloidosis affects 25% of the very aged and associates with genetic variation in alpha2-macroglobulin and tau: a population-based autopsy study". Ann. Med. 40 (3): 232–9. doi:10.1080/07853890701842988. PMID 18382889.