SEMA6C

From Wikipedia, the free encyclopedia


Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
Identifiers
Symbol(s) SEMA6C; SEMAY; m-Sema Y; m-Sema Y2
External IDs OMIM: 609294 MGI1338032 HomoloGene7931
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 10500 20360
Ensembl ENSG00000143434 ENSMUSG00000038777
Uniprot Q9H3T2 Q3TU06
Refseq NM_030913 (mRNA)
NP_112175 (protein)
NM_011351 (mRNA)
NP_035481 (protein)
Location Chr 1: 149.37 - 149.39 Mb Chr 3: 95.25 - 95.26 Mb
Pubmed search [1] [2]

Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C, also known as SEMA6C, is a human gene.[1]

This gene product is a member of the semaphorin family of proteins. Semaphorins represent important molecular signals controlling multiple aspects of the cellular response that follows CNS injury, and thus may play an important role in neural regeneration.[1]

[edit] References

[edit] Further reading

  • Pasterkamp RJ, Verhaagen J (2001). "Emerging roles for semaphorins in neural regeneration.". Brain Res. Brain Res. Rev. 35 (1): 36–54. PMID 11245885. 
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414. 
  • Imabayashi H, Mori T, Gojo S, et al. (2003). "Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis.". Exp. Cell Res. 288 (1): 35–50. PMID 12878157. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Qu X, Wei H, Zhai Y, et al. (2002). "Identification, characterization, and functional study of the two novel human members of the semaphorin gene family.". J. Biol. Chem. 277 (38): 35574–85. doi:10.1074/jbc.M206451200. PMID 12110693. 
  • Nagase T, Nakayama M, Nakajima D, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 8 (2): 85–95. PMID 11347906. 
  • Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. PMID 9110174. 
  • Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.