SEMA4F

From Wikipedia, the free encyclopedia

Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F

Identifiers

SEMA4F; M-SEMA; PRO2353; SEMAM; SEMAW; m-Sema M; m-Sema-M

External IDs

OMIM: 603706 MGI: 1340055 HomoloGene: 3147

Gene ontology
Molecular Function:	• receptor activity • protein binding
Cellular Component:	• membrane fraction • endoplasmic reticulum • plasma membrane • integral to plasma membrane
Biological Process:	• cell-cell signaling • multicellular organismal development • nervous system development • axon guidance • cell differentiation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_004263 (mRNA)
NP_004254 (protein)

NM_011350 (mRNA)
NP_035480 (protein)

Location

Chr 2: 74.73 - 74.76 Mb

Chr 6: 82.88 - 82.91 Mb

Pubmed search

[1]

[2]

Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F, also known as SEMA4F, is a human gene.^[1]

[edit] References

^ Entrez Gene: SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F.

[edit] Further reading

Giger RJ, Urquhart ER, Gillespie SK, et al. (1999). "Neuropilin-2 is a receptor for semaphorin IV: insight into the structural basis of receptor function and specificity.". Neuron 21 (5): 1079–92. PMID 9856463.
Encinas JA, Kikuchi K, Chedotal A, et al. (1999). "Cloning, expression, and genetic mapping of Sema W, a member of the semaphorin family.". Proc. Natl. Acad. Sci. U.S.A. 96 (5): 2491–6. PMID 10051670.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMID 11256614.
Schultze W, Eulenburg V, Lessmann V, et al. (2001). "Semaphorin4F interacts with the synapse-associated protein SAP90/PSD-95.". J. Neurochem. 78 (3): 482–9. PMID 11483650.
Francks C, Fisher SE, Olson RK, et al. (2002). "Fine mapping of the chromosome 2p12-16 dyslexia susceptibility locus: quantitative association analysis and positional candidate genes SEMA4F and OTX1.". Psychiatr. Genet. 12 (1): 35–41. PMID 11901358.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901.