SEMA3C

From Wikipedia, the free encyclopedia

Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C

Identifiers

SEMA3C; SEMAE; SemE

External IDs

OMIM: 602645 MGI: 107557 HomoloGene: 36201

Gene ontology
Molecular Function:	• semaphorin receptor binding
Cellular Component:	• extracellular space
Biological Process:	• immune response • transmembrane receptor protein tyrosine kinase signaling pathway • multicellular organismal development • response to drug

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_006379 (mRNA)
NP_006370 (protein)

NM_013657 (mRNA)
NP_038685 (protein)

Location

Chr 7: 80.21 - 80.39 Mb

Chr 5: 17.09 - 17.24 Mb

Pubmed search

[1]

[2]

Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C, also known as SEMA3C, is a human gene.^[1]

[edit] References

^ Entrez Gene: SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C.

[edit] Further reading

Püschel AW, Adams RH, Betz H (1995). "Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension.". Neuron 14 (5): 941–8. PMID 7748561.
Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, et al. (1995). "Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening.". Genomics 23 (1): 42–50. doi:10.1006/geno.1994.1457. PMID 7829101.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. PMID 8889548.
Mangasser-Stephan K, Dooley S, Welter C, et al. (1997). "Identification of human semaphorin E gene expression in rheumatoid synovial cells by mRNA differential display.". Biochem. Biophys. Res. Commun. 234 (1): 153–6. doi:10.1006/bbrc.1997.6607. PMID 9168980.
Chen H, Chédotal A, He Z, et al. (1997). "Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III.". Neuron 19 (3): 547–59. PMID 9331348.
Yamada T, Endo R, Gotoh M, Hirohashi S (1998). "Identification of semaphorin E as a non-MDR drug resistance gene of human cancers.". Proc. Natl. Acad. Sci. U.S.A. 94 (26): 14713–8. PMID 9405678.
Galani E, Sgouros J, Petropoulou C, et al. (2002). "Correlation of MDR-1, nm23-H1 and H Sema E gene expression with histopathological findings and clinical outcome in ovarian and breast cancer patients.". Anticancer Res. 22 (4): 2275–80. PMID 12174914.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMID 12690205.
Rieger J, Wick W, Weller M (2003). "Human malignant glioma cells express semaphorins and their receptors, neuropilins and plexins.". Glia 42 (4): 379–89. doi:10.1002/glia.10210. PMID 12730958.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
Miller LE, Weidler C, Falk W, et al. (2004). "Increased prevalence of semaphorin 3C, a repellent of sympathetic nerve fibers, in the synovial tissue of patients with rheumatoid arthritis.". Arthritis Rheum. 50 (4): 1156–63. doi:10.1002/art.20110. PMID 15077297.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Beckers J, Herrmann F, Rieger S, et al. (2005). "Identification and validation of novel ERBB2 (HER2, NEU) targets including genes involved in angiogenesis.". Int. J. Cancer 114 (4): 590–7. doi:10.1002/ijc.20798. PMID 15609325.
Herman JG, Meadows GG (2007). "Increased class 3 semaphorin expression modulates the invasive and adhesive properties of prostate cancer cells.". Int. J. Oncol. 30 (5): 1231–8. PMID 17390026.