SEC24C

From Wikipedia, the free encyclopedia

SEC24 related gene family, member C (S. cerevisiae)

Identifiers

SEC24C; KIAA0079

External IDs

OMIM: 607185 MGI: 1919746 HomoloGene: 3615

Gene ontology
Molecular Function:	• molecular_function • protein binding • zinc ion binding
Cellular Component:	• endoplasmic reticulum • COPII vesicle coat
Biological Process:	• intracellular protein transport • ER to Golgi vesicle-mediated transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_004922 (mRNA)
NP_004913 (protein)

NM_172596 (mRNA)
NP_766184 (protein)

Location

Chr 10: 75.17 - 75.2 Mb

Chr 14: 19.46 - 19.59 Mb

Pubmed search

[1]

[2]

SEC24 related gene family, member C (S. cerevisiae), also known as SEC24C, is a human gene.^[1]

The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration. Alternatively spliced transcript variants encoding the same protein have been identified.^[1]

[edit] References

^ ^a ^b Entrez Gene: SEC24C SEC24 related gene family, member C (S. cerevisiae).

[edit] Further reading

Nomura N, Nagase T, Miyajima N, et al. (1995). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.". DNA Res. 1 (5): 223–9. PMID 7584044.
Pagano A, Letourneur F, Garcia-Estefania D, et al. (1999). "Sec24 proteins and sorting at the endoplasmic reticulum.". J. Biol. Chem. 274 (12): 7833–40. PMID 10075675.
Tani K, Oyama Y, Hatsuzawa K, Tagaya M (1999). "Hypothetical protein KIAA0079 is a mammalian homologue of yeast Sec24p.". FEBS Lett. 447 (2-3): 247–50. PMID 10214955.
Tang BL, Kausalya J, Low DY, et al. (1999). "A family of mammalian proteins homologous to yeast Sec24p.". Biochem. Biophys. Res. Commun. 258 (3): 679–84. doi:10.1006/bbrc.1999.0574. PMID 10329445.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Dudognon P, Maeder-Garavaglia C, Carpentier JL, Paccaud JP (2004). "Regulation of a COPII component by cytosolic O-glycosylation during mitosis.". FEBS Lett. 561 (1-3): 44–50. doi:10.1016/S0014-5793(04)00109-7. PMID 15013749.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.