SEC22B

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SEC22 vesicle trafficking protein homolog B (S. cerevisiae)
PDB rendering based on 1ifq.
Available structures: 1ifq, 2nup, 2nut
Identifiers
Symbol(s) SEC22B; ERS-24; SEC22L1
External IDs OMIM: 604029 MGI: 1338759 HomoloGene: 3597
Orthologs
Human Mouse
Entrez 9554 20333
Ensembl n/a ENSMUSG00000027879
Uniprot n/a Q3UZ06
Refseq NM_004892 (mRNA)
NP_004883 (protein)		 NM_011342 (mRNA)
NP_035472 (protein)
Location n/a Chr 3: 97.99 - 98.01 Mb
Pubmed search [1] [2]

SEC22 vesicle trafficking protein homolog B (S. cerevisiae), also known as SEC22B, is a human gene.[1]

The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins. There is evidence for use of multiple polyadenylation sites for the transcript.[1]

[edit] References

  1. ^ a b Entrez Gene: SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae).

[edit] Further reading

  • Chi A, Valencia JC, Hu ZZ, et al. (2007). "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.". J. Proteome Res. 5 (11): 3135–44. doi:10.1021/pr060363j. PMID 17081065. 
  • Okumura AJ, Hatsuzawa K, Tamura T, et al. (2006). "Involvement of a novel Q-SNARE, D12, in quality control of the endomembrane system.". J. Biol. Chem. 281 (7): 4495–506. doi:10.1074/jbc.M509715200. PMID 16354670. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Breuza L, Halbeisen R, Jenö P, et al. (2004). "Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46.". J. Biol. Chem. 279 (45): 47242–53. doi:10.1074/jbc.M406644200. PMID 15308636. 
  • Nakajima K, Hirose H, Taniguchi M, et al. (2005). "Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion.". EMBO J. 23 (16): 3216–26. doi:10.1038/sj.emboj.7600333. PMID 15272311. 
  • Fu GK, Wang JT, Yang J, et al. (2005). "Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.". Genomics 84 (1): 205–10. doi:10.1016/j.ygeno.2004.01.011. PMID 15203218. 
  • Hirose H, Arasaki K, Dohmae N, et al. (2005). "Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi.". EMBO J. 23 (6): 1267–78. doi:10.1038/sj.emboj.7600135. PMID 15029241. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546–60. PMID 11042152. 
  • Xu D, Joglekar AP, Williams AL, Hay JC (2001). "Subunit structure of a mammalian ER/Golgi SNARE complex.". J. Biol. Chem. 275 (50): 39631–9. doi:10.1074/jbc.M007684200. PMID 11035026. 
  • Parlati F, McNew JA, Fukuda R, et al. (2000). "Topological restriction of SNARE-dependent membrane fusion.". Nature 407 (6801): 194–8. doi:10.1038/35025076. PMID 11001058. 
  • Mao M, Fu G, Wu JS, et al. (1998). "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning.". Proc. Natl. Acad. Sci. U.S.A. 95 (14): 8175–80. PMID 9653160. 
  • Hay JC, Chao DS, Kuo CS, Scheller RH (1997). "Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells.". Cell 89 (1): 149–58. PMID 9094723. 
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