SDPR

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Serum deprivation response (phosphatidylserine binding protein)
Identifiers
Symbol(s) SDPR; PS-p68; SDR
External IDs OMIM: 606728 MGI: 99513 HomoloGene: 3422
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 8436 20324
Ensembl ENSG00000168497 ENSMUSG00000045954
Uniprot O95810 Q63918
Refseq NM_004657 (mRNA)
NP_004648 (protein)		 NM_138741 (mRNA)
NP_620080 (protein)
Location Chr 2: 192.41 - 192.42 Mb Chr 1: 51.23 - 51.25 Mb
Pubmed search [1] [2]

Serum deprivation response (phosphatidylserine binding protein), also known as SDPR, is a human gene.[1]

This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein has also been shown to be a substrate for protein kinase C (PKC) phosphorylation.[1]

[edit] References

  1. ^ a b Entrez Gene: SDPR serum deprivation response (phosphatidylserine binding protein).

[edit] Further reading

  • Burgener R, Wolf M, Ganz T, Baggiolini M (1990). "Purification and characterization of a major phosphatidylserine-binding phosphoprotein from human platelets.". Biochem. J. 269 (3): 729–34. PMID 2390065. 
  • Cross SH, Charlton JA, Nan X, Bird AP (1994). "Purification of CpG islands using a methylated DNA binding column.". Nat. Genet. 6 (3): 236–44. doi:10.1038/ng0394-236. PMID 8012384. 
  • Gustincich S, Schneider C (1993). "Serum deprivation response gene is induced by serum starvation but not by contact inhibition.". Cell Growth Differ. 4 (9): 753–60. PMID 8241023. 
  • Mineo C, Ying YS, Chapline C, et al. (1998). "Targeting of protein kinase Calpha to caveolae.". J. Cell Biol. 141 (3): 601–10. PMID 9566962. 
  • Gustincich S, Vatta P, Goruppi S, et al. (1999). "The human serum deprivation response gene (SDPR) maps to 2q32-q33 and codes for a phosphatidylserine-binding protein.". Genomics 57 (1): 120–9. doi:10.1006/geno.1998.5733. PMID 10191091. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801. 
  • Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
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