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Scyene was a small town in East Central Dallas County, Texas (USA), 10 miles east-southeast of downtown Dallas. It is now a neighborhood in East Dallas, just west of Mesquite and I-635. The town lay approximately within North Masters Drive on the east, Military Parkway on the north, North Prairie Creek Road on the west, and Bruton Road on the south. The center of the town was located at the intersection of Scyene Road and North Saint Augustine Drive (9600 Scyene Rd. & 3000 N. St. Augustine Dr.).
Scyene was officially established in 1854 when a post office was built in the city. Prior to that the town had been called either Thorpville or Prairie Creek. The town name was suggested by James Beeman with the spelling of "Seine", but residents first spelled it Sceyne, which eventually changed to Scyene.
The town was notable for residents Jesse and Frank James, Cole and Bob Younger, and Myra Shirley (Belle) Starr, who moved to Scyene during the Civil War, in 1864.
At its zenith, in 1873, Scyene had a population of around 300, a Masonic Lodge, a wagon factory, and six saloons. That same year, however, the Texas and Pacific Railway bypassed the town, causing a slow decline of the town into today's Dallas neighborhood.
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