SCN7A

From Wikipedia, the free encyclopedia


Sodium channel, voltage-gated, type VII, alpha
Identifiers
Symbol(s) SCN7A; SCN6A
External IDs OMIM: 182392 MGI: 102965 HomoloGene: 55706
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 6332 20272
Ensembl ENSG00000136546 ENSMUSG00000034810
Uniprot Q01118 n/a
Refseq NM_002976 (mRNA)
NP_002967 (protein)		 NM_009135 (mRNA)
NP_033161 (protein)
Location Chr 2: 166.97 - 167.05 Mb Chr 2: 66.47 - 66.59 Mb
Pubmed search [1] [2]

Sodium channel, voltage-gated, type VII, alpha, also known as SCN7A, is a human gene.[1]


Contents

[edit] See also

[edit] References

  1. ^ Entrez Gene: SCN7A sodium channel, voltage-gated, type VII, alpha.

[edit] Further reading

  • Plummer NW, Meisler MH (1999). "Evolution and diversity of mammalian sodium channel genes.". Genomics 57 (2): 323-31. doi:10.1006/geno.1998.5735. PMID 10198179. 
  • Meyers KJ, Mosley TH, Fox E, et al. (2007). "Genetic variations associated with echocardiographic left ventricular traits in hypertensive blacks.". Hypertension 49 (5): 992-9. doi:10.1161/HYPERTENSIONAHA.106.081265. PMID 17339538. 
  • Zhang KX, Zhu DL, He X, et al. (2004). "[Association of single nucleotide polymorphism in human SCN7A gene with essential hypertension in Chinese]". Zhonghua Yi Xue Yi Chuan Xue Za Zhi 20 (6): 463-7. PMID 14669210. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Goldin AL, Barchi RL, Caldwell JH, et al. (2001). "Nomenclature of voltage-gated sodium channels.". Neuron 28 (2): 365-8. PMID 11144347. 
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791-806. PMID 8889548. 
  • George AL, Knops JF, Han J, et al. (1994). "Assignment of a human voltage-dependent sodium channel alpha-subunit gene (SCN6A) to 2q21-q23.". Genomics 19 (2): 395-7. PMID 8188276. 
  • Boyle MB, Heslip LA (1995). "Voltage-dependent Na+ channel mRNA expression in pregnant myometrium.". Recept. Channels 2 (3): 249-53. PMID 7874451. 
  • Han JA, Lu CM, Brown GB, Rado TA (1991). "Direct amplification of a single dissected chromosomal segment by polymerase chain reaction: a human brain sodium channel gene is on chromosome 2q22-q23.". Proc. Natl. Acad. Sci. U.S.A. 88 (2): 335-9. PMID 1846440. 
  • George AL, Knittle TJ, Tamkun MM (1992). "Molecular cloning of an atypical voltage-gated sodium channel expressed in human heart and uterus: evidence for a distinct gene family.". Proc. Natl. Acad. Sci. U.S.A. 89 (11): 4893-7. PMID 1317577. 

[edit] External links

 This membrane protein-related article is a stub. You can help Wikipedia by expanding it.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

v • d • e
Membrane transport protein: ion channels
Ca2+: Calcium channel
Na+: Sodium channel
Navα (1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.9, 7A) • Navβ (1, 2, 3, 4) • Epithelial sodium channel
K+: Potassium channel
Cl-: Chloride channel
Porin
Cations: TRP
TRPA (1) • TRPC (1, 2, 3, 4, 4AP, 5, 6, 7) • TRPM (1, 2, 3, 4, 5, 6, 7, 8) • TRPML (Mucolipin-1) • TRPP (1, 2) • TRPV (1, 2, 3, 4, 5, 6)
Other/general