SCAMP3

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Secretory carrier membrane protein 3
Identifiers
Symbol(s) SCAMP3; C1orf3
External IDs OMIM: 606913 MGI: 1346346 HomoloGene: 4164
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 10067 24045
Ensembl ENSG00000116521 ENSMUSG00000028049
Uniprot O14828 Q3TUV6
Refseq NM_005698 (mRNA)
NP_005689 (protein)		 NM_011886 (mRNA)
NP_036016 (protein)
Location Chr 1: 153.49 - 153.5 Mb Chr 3: 89.26 - 89.27 Mb
Pubmed search [1] [2]

Secretory carrier membrane protein 3, also known as SCAMP3, is a human gene.[1]

This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways. Two transcript variants encoding different isoforms have been found for this gene.[1]

[edit] References

  1. ^ a b Entrez Gene: SCAMP3 secretory carrier membrane protein 3.

[edit] Further reading

  • Wu TT, Castle JD (1997). "Evidence for colocalization and interaction between 37 and 39 kDa isoforms of secretory carrier membrane proteins (SCAMPs).". J. Cell. Sci. 110 ( Pt 13): 1533–41. PMID 9224770. 
  • Winfield SL, Tayebi N, Martin BM, et al. (1997). "Identification of three additional genes contiguous to the glucocerebrosidase locus on chromosome 1q21: implications for Gaucher disease.". Genome Res. 7 (10): 1020–6. PMID 9331372. 
  • Singleton DR, Wu TT, Castle JD (1997). "Three mammalian SCAMPs (secretory carrier membrane proteins) are highly related products of distinct genes having similar subcellular distributions.". J. Cell. Sci. 110 ( Pt 17): 2099–107. PMID 9378760. 
  • Wu TT, Castle JD (1999). "Tyrosine phosphorylation of selected secretory carrier membrane proteins, SCAMP1 and SCAMP3, and association with the EGF receptor.". Mol. Biol. Cell 9 (7): 1661–74. PMID 9658162. 
  • Fernández-Chacón R, Achiriloaie M, Janz R, et al. (2000). "SCAMP1 function in endocytosis.". J. Biol. Chem. 275 (17): 12752–6. PMID 10777571. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
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