SCAMP1

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Secretory carrier membrane protein 1
Identifiers
Symbol(s) SCAMP1; SCAMP; SCAMP37
External IDs OMIM: 606911 MGI: 1349480 HomoloGene: 37975
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 9522 107767
Ensembl ENSG00000085365 ENSMUSG00000021687
Uniprot O15126 Q3TD71
Refseq NM_052822 (mRNA)
NP_438173 (protein)		 NM_029153 (mRNA)
NP_083429 (protein)
Location Chr 5: 77.69 - 77.81 Mb Chr 13: 95.3 - 95.39 Mb
Pubmed search [1] [2]

Secretory carrier membrane protein 1, also known as SCAMP1, is a human gene.[1]

This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways.[1]

[edit] References

  1. ^ a b Entrez Gene: SCAMP1 secretory carrier membrane protein 1.

[edit] Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Brand SH, Castle JD (1993). "SCAMP 37, a new marker within the general cell surface recycling system.". EMBO J. 12 (10): 3753–61. PMID 8404846. 
  • Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474. 
  • Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. PMID 9110174. 
  • Wu TT, Castle JD (1997). "Evidence for colocalization and interaction between 37 and 39 kDa isoforms of secretory carrier membrane proteins (SCAMPs).". J. Cell. Sci. 110 ( Pt 13): 1533–41. PMID 9224770. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Singleton DR, Wu TT, Castle JD (1997). "Three mammalian SCAMPs (secretory carrier membrane proteins) are highly related products of distinct genes having similar subcellular distributions.". J. Cell. Sci. 110 ( Pt 17): 2099–107. PMID 9378760. 
  • Mao M, Fu G, Wu JS, et al. (1998). "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning.". Proc. Natl. Acad. Sci. U.S.A. 95 (14): 8175–80. PMID 9653160. 
  • Wu TT, Castle JD (1999). "Tyrosine phosphorylation of selected secretory carrier membrane proteins, SCAMP1 and SCAMP3, and association with the EGF receptor.". Mol. Biol. Cell 9 (7): 1661–74. PMID 9658162. 
  • Fernández-Chacón R, Achiriloaie M, Janz R, et al. (2000). "SCAMP1 function in endocytosis.". J. Biol. Chem. 275 (17): 12752–6. PMID 10777571. 
  • Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546–60. PMID 11042152. 
  • Bell AW, Ward MA, Blackstock WP, et al. (2001). "Proteomics characterization of abundant Golgi membrane proteins.". J. Biol. Chem. 276 (7): 5152–65. doi:10.1074/jbc.M006143200. PMID 11042173. 
  • Fernández-Chacón R, Südhof TC (2001). "Novel SCAMPs lacking NPF repeats: ubiquitous and synaptic vesicle-specific forms implicate SCAMPs in multiple membrane-trafficking functions.". J. Neurosci. 20 (21): 7941–50. PMID 11050114. 
  • Guo Z, Liu L, Cafiso D, Castle D (2002). "Perturbation of a very late step of regulated exocytosis by a secretory carrier membrane protein (SCAMP2)-derived peptide.". J. Biol. Chem. 277 (38): 35357–63. doi:10.1074/jbc.M202259200. PMID 12124380. 
  • Liu L, Guo Z, Tieu Q, et al. (2003). "Role of secretory carrier membrane protein SCAMP2 in granule exocytosis.". Mol. Biol. Cell 13 (12): 4266–78. doi:10.1091/mbc.E02-03-0136. PMID 12475951. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Hillman RT, Green RE, Brenner SE (2005). "An unappreciated role for RNA surveillance.". Genome Biol. 5 (2): R8. doi:10.1186/gb-2004-5-2-r8. PMID 14759258. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Lin PJ, Williams WP, Luu Y, et al. (2005). "Secretory carrier membrane proteins interact and regulate trafficking of the organellar (Na+,K+)/H+ exchanger NHE7.". J. Cell. Sci. 118 (Pt 9): 1885–97. doi:10.1242/jcs.02315. PMID 15840657. 
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