SC65

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Synaptonemal complex protein SC65
Identifiers
Symbol(s) SC65; NOL55
External IDs MGI: 1913430 HomoloGene: 4713
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 10609 66180
Ensembl ENSG00000141696 ENSMUSG00000006931
Uniprot Q92791 n/a
Refseq NM_006455 (mRNA)
NP_006446 (protein)		 XM_982688 (mRNA)
XP_987782 (protein)
Location Chr 17: 37.21 - 37.22 Mb Chr 11: 100.22 - 100.23 Mb
Pubmed search [1] [2]

Synaptonemal complex protein SC65, also known as SC65, is a human gene.[1]

This nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes.[1]

[edit] References

  1. ^ a b Entrez Gene: SC65 synaptonemal complex protein SC65.

[edit] Further reading

  • Foster LJ, Rudich A, Talior I, et al. (2006). "Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC).". J. Proteome Res. 5 (1): 64–75. doi:10.1021/pr0502626. PMID 16396496. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Fosså A, Siebert R, Aasheim HC, et al. (2000). "Identification of nucleolar protein No55 as a tumour-associated autoantigen in patients with prostate cancer.". Br. J. Cancer 83 (6): 743–9. doi:10.1054/bjoc.2000.1365. PMID 10952778. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Ochs RL, Stein TW, Chan EK, et al. (1996). "cDNA cloning and characterization of a novel nucleolar protein.". Mol. Biol. Cell 7 (7): 1015–24. PMID 8862517. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
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