SBF1

From Wikipedia, the free encyclopedia

SET binding factor 1

PDB rendering based on 1v5u.

Available structures: 1v5u

Identifiers

Symbol(s)

SBF1; DKFZp761D0422; MGC99700; MTMR5

External IDs

OMIM: 603560 MGI: 1925230 HomoloGene: 84710

Gene ontology
Molecular Function:	• inositol or phosphatidylinositol phosphatase activity • protein tyrosine/serine/threonine phosphatase activity
Cellular Component:	• nucleus • integral to membrane
Biological Process:	• protein amino acid dephosphorylation • phospholipid dephosphorylation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_002972 (mRNA)
NP_002963 (protein)

XM_001002810 (mRNA)
XP_001002810 (protein)

Location

Chr 22: 49.23 - 49.26 Mb

Chr 15: 89.12 - 89.14 Mb

Pubmed search

[1]

[2]

SET binding factor 1, also known as SBF1, is a human gene.^[1]

[edit] References

^ Entrez Gene: SBF1 SET binding factor 1.

[edit] Further reading

Cui X, De Vivo I, Slany R, et al. (1998). "Association of SET domain and myotubularin-related proteins modulates growth control.". Nat. Genet. 18 (4): 331–7. doi:10.1038/ng0498-331. PMID 9537414.
Laporte J, Blondeau F, Buj-Bello A, et al. (1998). "Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human.". Hum. Mol. Genet. 7 (11): 1703–12. PMID 9736772.
Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22.". Nature 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
Firestein R, Cui X, Huie P, Cleary ML (2000). "Set domain-dependent regulation of transcriptional silencing and growth control by SUV39H1, a mammalian ortholog of Drosophila Su(var)3-9.". Mol. Cell. Biol. 20 (13): 4900–9. PMID 10848615.
Firestein R, Cleary ML (2002). "Pseudo-phosphatase Sbf1 contains an N-terminal GEF homology domain that modulates its growth regulatory properties.". J. Cell. Sci. 114 (Pt 16): 2921–7. PMID 11686296.
Firestein R, Nagy PL, Daly M, et al. (2002). "Male infertility, impaired spermatogenesis, and azoospermia in mice deficient for the pseudophosphatase Sbf1.". J. Clin. Invest. 109 (9): 1165–72. PMID 11994405.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Kim SA, Vacratsis PO, Firestein R, et al. (2003). "Regulation of myotubularin-related (MTMR)2 phosphatidylinositol phosphatase by MTMR5, a catalytically inactive phosphatase.". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4492–7. doi:10.1073/pnas.0431052100. PMID 12668758.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.