SARDH

From Wikipedia, the free encyclopedia

Sarcosine dehydrogenase

Identifiers

SARDH; DMGDHL1; FLJ36475; SAR; SARD; SDH

External IDs

OMIM: 604455 MGI: 2183102 HomoloGene: 5149

Gene ontology
Molecular Function:	• aminomethyltransferase activity • sarcosine dehydrogenase activity • electron carrier activity • oxidoreductase activity
Cellular Component:	• cytoplasm • mitochondrion • mitochondrial matrix
Biological Process:	• electron transport • glycine catabolic process • biological_process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_007101 (mRNA)
NP_009032 (protein)

NM_138665 (mRNA)
NP_619606 (protein)

Location

Chr 9: 135.52 - 135.59 Mb

Chr 2: 27.01 - 27.07 Mb

Pubmed search

[1]

[2]

Sarcosine dehydrogenase, also known as SARDH, is a human gene.^[1]

[edit] References

^ Entrez Gene: SARDH sarcosine dehydrogenase.

[edit] Further reading

Porter DH, Cook RJ, Wagner C (1986). "Enzymatic properties of dimethylglycine dehydrogenase and sarcosine dehydrogenase from rat liver.". Arch. Biochem. Biophys. 243 (2): 396–407. PMID 2417560.
London RE, Gabel SA, Funk A (1988). "Metabolism of excess methionine in the liver of intact rat: an in vivo 2H NMR study.". Biochemistry 26 (22): 7166–72. PMID 2447942.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Bergeron F, Otto A, Blache P, et al. (1998). "Molecular cloning and tissue distribution of rat sarcosine dehydrogenase.". Eur. J. Biochem. 257 (3): 556–61. PMID 9839943.
Eschenbrenner M, Jorns MS (1999). "Cloning and mapping of the cDNA for human sarcosine dehydrogenase, a flavoenzyme defective in patients with sarcosinemia.". Genomics 59 (3): 300–8. doi:10.1006/geno.1999.5886. PMID 10444331.
Gilbert JR, Kumar A, Newey S, et al. (2000). "Physical and cDNA mapping in the DBH region of human chromosome 9q34.". Hum. Hered. 50 (3): 151–7. PMID 10686491.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.