Salutaridinol 7-O-acetyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a salutaridinol 7-O-acetyltransferase (EC 2.3.1.150) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + salutaridinol CoA + 7-O-acetylsalutaridinol

Thus, the two substrates of this enzyme are acetyl-CoA and salutaridinol, whereas its two products are CoA and 7-O-acetylsalutaridinol.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:salutaridinol 7-O-acetyltransferase. This enzyme participates in alkaloid biosynthesis i.

[edit] References

• IUBMB entry for 2.3.1.150
• BRENDA references for 2.3.1.150 (Recommended.)
• PubMed references for 2.3.1.150
• PubMed Central references for 2.3.1.150
• Google Scholar references for 2.3.1.150
• Lenz R, Zenk MH (1994). "Closure of the oxide bridge in morphine biosynthesis". Tetrahedron Lett. 35: 3897–3900. doi:10.1016/S0040-4039(00)76696-2. 
• Lenz R, Zenk MH (1995). "Acetyl coenzyme A:salutaridinol-7-O-acetyltransferase from papaver somniferum plant cell cultures. The enzyme catalyzing the formation of thebaine in morphine biosynthesis". J. Biol. Chem. 270: 31091–6. doi:10.1074/jbc.270.52.31091. PMID 8537369. 

[edit] External links

The CAS registry number for this enzyme class is 156859-13-1.

• IUBMB entry for 2.3.1.150

• KEGG entry for 2.3.1.150

• BRENDA entry for 2.3.1.150

• NiceZyme view of 2.3.1.150

• EC2PDB: PDB structures for 2.3.1.150

• PRIAM entry for 2.3.1.150

• PUMA2 entry for 2.3.1.150

• IntEnz: Integrated Enzyme entry for 2.3.1.150

• MetaCyc entry for 2.3.1.150

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047180: salutaridinol 7-O-acetyltransferase

• AMIGO entry for GO code 0047180: salutaridinol 7-O-acetyltransferase