Salutaridine reductase (NADPH)

From Wikipedia, the free encyclopedia

In enzymology, a salutaridine reductase (NADPH) (EC 1.1.1.248) is an enzyme that catalyzes the chemical reaction

salutaridinol + NADP⁺ salutaridine + NADPH + H⁺

Thus, the two substrates of this enzyme are salutaridinol and NADP⁺, whereas its 3 products are salutaridine, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is salutaridinol:NADP+ 7-oxidoreductase. This enzyme participates in alkaloid biosynthesis i.

[edit] References

• IUBMB entry for 1.1.1.248
• BRENDA references for 1.1.1.248 (Recommended.)
• PubMed references for 1.1.1.248
• PubMed Central references for 1.1.1.248
• Google Scholar references for 1.1.1.248
• Gerady R and Zenk MH (1993). "Purification and characterization of salutaridine:NADPH 7-oxidoreductase from Papaver somniferum". Phytochemistry 34: 125–132. doi:10.1016/S0031-9422(00)90793-3. 

[edit] External links

The CAS registry number for this enzyme class is 152743-95-8.

• IUBMB entry for 1.1.1.248

• KEGG entry for 1.1.1.248

• BRENDA entry for 1.1.1.248

• NiceZyme view of 1.1.1.248

• EC2PDB: PDB structures for 1.1.1.248

• PRIAM entry for 1.1.1.248

• PUMA2 entry for 1.1.1.248

• IntEnz: Integrated Enzyme entry for 1.1.1.248

• MetaCyc entry for 1.1.1.248

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047037: salutaridine reductase (NADPH)

• AMIGO entry for GO code 0047037: salutaridine reductase (NADPH)