S100G

From Wikipedia, the free encyclopedia


S100 calcium binding protein G
Identifiers
Symbol(s) S100G; CABP1; CABP9K; CALB3; MGC138379
External IDs OMIM: 302020 MGI: 104528 HomoloGene: 36150
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 795 12309
Ensembl ENSG00000169906 ENSMUSG00000040808
Uniprot P29377 Q5VM59
Refseq NM_004057 (mRNA)
NP_004048 (protein)		 NM_009789 (mRNA)
NP_033919 (protein)
Location Chr X: 16.58 - 16.58 Mb Chr X: 158.31 - 158.31 Mb
Pubmed search [1] [2]

S100 calcium binding protein G, also known as S100G, is a human gene.[1]

This gene encodes calbindin D9K, a vitamin D-dependent calcium-binding protein. This cytosolic protein belongs to a family of calcium-binding proteins that includes calmodulin, parvalbumin, troponin C, and S100 protein. In the intestine, the protein is vitamin D-dependent and its expression correlates with calcium transport activity. The protein may increase Ca2+ absorption by buffering Ca2+ in the cytoplasm and increase ATP-dependent Ca2+ transport in duodenal basolateral membrane vesicles.[1]

[edit] References

  1. ^ a b Entrez Gene: S100G S100 calcium binding protein G.

[edit] Further reading

  • Balmain N (1991). "Calbindin-D9k. A vitamin-D-dependent, calcium-binding protein in mineralized tissues.". Clin. Orthop. Relat. Res. (265): 265–76. PMID 2009668. 
  • Jeung EB, Krisinger J, Dann JL, Leung PC (1992). "Molecular cloning of the full-length cDNA encoding the human calbindin-D9k.". FEBS Lett. 307 (2): 224–8. PMID 1379540. 
  • Howard A, Legon S, Spurr NK, Walters JR (1992). "Molecular cloning and chromosomal assignment of human calbindin-D9k.". Biochem. Biophys. Res. Commun. 185 (2): 663–9. PMID 1610358. 
  • Fleet JC, Hock JM (1995). "Identification of osteocalcin mRNA in nonosteoid tissue of rats and humans by reverse transcription-polymerase chain reaction.". J. Bone Miner. Res. 9 (10): 1565–73. PMID 7817802. 
  • Miller EK, Word RA, Goodall CA, Iacopino AM (1994). "Calbindin-D9K gene expression in human myometrium during pregnancy and labor.". J. Clin. Endocrinol. Metab. 79 (2): 609–15. PMID 8045984. 
  • Jeung EB, Leung PC, Krisinger J (1994). "The human calbindin-D9k gene. Complete structure and implications on steroid hormone regulation.". J. Mol. Biol. 235 (4): 1231–8. doi:10.1006/jmbi.1994.1076. PMID 8308886. 
  • Barley NF, Prathalingam SR, Zhi P, et al. (1999). "Factors involved in the duodenal expression of the human calbindin-D9k gene.". Biochem. J. 341 ( Pt 3): 491–500. PMID 10417310. 
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Wang L, Klopot A, Freund JN, et al. (2004). "Control of differentiation-induced calbindin-D9k gene expression in Caco-2 cells by cdx-2 and HNF-1alpha.". Am. J. Physiol. Gastrointest. Liver Physiol. 287 (5): G943–53. doi:10.1152/ajpgi.00121.2004. PMID 15217781. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome.". Nature 434 (7031): 325–37. doi:10.1038/nature03440. PMID 15772651. 
 This article on a gene on the X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it.