S-carboxymethylcysteine synthase

From Wikipedia, the free encyclopedia

In enzymology, a S-carboxymethylcysteine synthase (EC 4.5.1.5) is an enzyme that catalyzes the chemical reaction

3-chloro-L-alanine + thioglycolate S-carboxymethyl-L-cysteine + chloride

Thus, the two substrates of this enzyme are 3-chloro-L-alanine and thioglycolate, whereas its two products are S-carboxymethyl-L-cysteine and chloride.

This enzyme belongs to the family of lyases, specifically the class of carbon-halide lyases. The systematic name of this enzyme class is 3-chloro-L-alanine chloride-lyase (adding thioglycolate S-carboxymethyl-L-cysteine-forming). This enzyme is also called S-carboxymethyl-L-cysteine synthase. It employs one cofactor, pyridoxal phosphate.

[edit] References

• IUBMB entry for 4.5.1.5
• BRENDA references for 4.5.1.5 (Recommended.)
• PubMed references for 4.5.1.5
• PubMed Central references for 4.5.1.5
• Google Scholar references for 4.5.1.5
• Kumagai H, Suzuki H, Shigematsu H and Tuchikura T (1989). "S-Carboxymethylcysteine synthase from Escherichia coli". Agric. Biol. Chem. 53: 2481–2487. 

[edit] External links

The CAS registry number for this enzyme class is 124671-39-2.

• IUBMB entry for 4.5.1.5

• KEGG entry for 4.5.1.5

• BRENDA entry for 4.5.1.5

• NiceZyme view of 4.5.1.5

• EC2PDB: PDB structures for 4.5.1.5

• PRIAM entry for 4.5.1.5

• PUMA2 entry for 4.5.1.5

• IntEnz: Integrated Enzyme entry for 4.5.1.5

• MetaCyc entry for 4.5.1.5

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050272: S-carboxymethylcysteine synthase

• AMIGO entry for GO code 0050272: S-carboxymethylcysteine synthase