From Wikipedia, the free encyclopedia
| RyeE RNA |
 |
| Type: |
Gene; sRNA; |
| 2° structure: |
Predicted; PFOLD |
| Seed alignment: |
Gottesman S, Storz G |
| Avg length: |
84.8 nucleotides |
| Avg identity: |
80% |
|
The CyaR RNA (formerly known as RyeE RNA) non-coding RNA was identified in a large scale screen of E. coli and was called candidate 14.[1] The exact 5' and 3' ends of this RNA are uncertain. This gene lies between yegQ and orgK in E. coli. This small RNA was shown to be bound by the Hfq protein. This RNA has been renamed as CyaR for (cyclic AMP-activated RNA). It has recently been shown that CyaR RNA acts as a repressor of the porin OmpX.[2] It has also been shown that cyaR expression is tightly controlled by the cyclic AMP receptor protein, CRP.[2]
[edit] References
- ^ Wassarman, KM; Repoila F, Rosenow C, Storz G, Gottesman S (2001). "Identification of novel small RNAs using comparative genomics and microarrays". Genes Dev 15: 1637–1651. doi:10.1101/gad.901001. PMID 11445539.
- ^ a b Papenfort K, Pfeiffer V, Lucchini S, Sonawane A, Hinton JC, Vogel J (May 2008). "Systematic deletion of Salmonella small RNA genes identifies CyaR, a conserved CRP-dependent riboregulator of OmpX synthesis". Mol. Microbiol. 68 (4): 890–906. doi:10.1111/j.1365-2958.2008.06189.x. PMID 18399940.
[edit] External links
