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| RybB RNA |
 |
| Type: |
Gene; sRNA; |
| 2° structure: |
Predicted; PFOLD |
| Seed alignment: |
Gottesman S, Storz G |
| Avg length: |
79.5 nucleotides |
| Avg identity: |
89% |
|
RybB is a small non-coding RNA was identified in a large scale screen of E. coli.[1] The function of this short RNA has been studied using a transcriptomic approach and kinetic analyses of target mRNA decay in vivo. RybB was identified as a factor that selectively accelerates the decay of multiple major omp mRNAs upon induction of the envelope stress response.[2] This RNA has been shown to bind to the Hfq protein.
[edit] References
- ^ Wassarman, KM; Repoila F, Rosenow C, Storz G, Gottesman S (2001). "Identification of novel small RNAs using comparative genomics and microarrays". Genes Dev 15: 1637–1651. doi:10.1101/gad.901001. PMID 11445539.
- ^ Papenfort, K; Pfeiffer V, Mika F, Lucchini S, Hinton JC, Vogel J (2006). "SigmaE-dependent small RNAs of Salmonella respond to membrane stress by accelerating global omp mRNA decay". Mol Microbiol. 62: 1674–1688. doi:10.1111/j.1365-2958.2006.05524.x. PMID 17427289.
[edit] External links
