RUFY1

From Wikipedia, the free encyclopedia

RUN and FYVE domain containing 1

Identifiers

RUFY1; FLJ22251; RABIP4; ZFYVE12

External IDs

OMIM: 610327 MGI: 2429762 HomoloGene: 23522

Gene ontology
Molecular Function:	• protein binding • zinc ion binding • lipid binding • protein transporter activity • metal ion binding
Cellular Component:	• cytoplasm • membrane
Biological Process:	• protein transport • regulation of endocytosis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_001040451 (mRNA)
NP_001035541 (protein)

NM_172557 (mRNA)
NP_766145 (protein)

Location

Chr 5: 178.91 - 178.97 Mb

Chr 11: 50.23 - 50.27 Mb

Pubmed search

[1]

[2]

RUN and FYVE domain containing 1, also known as RUFY1, is a human gene.^[1]

[edit] References

^ Entrez Gene: RUFY1 RUN and FYVE domain containing 1.

[edit] Further reading

Cormont M, Mari M, Galmiche A, et al. (2001). "A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic.". Proc. Natl. Acad. Sci. U.S.A. 98 (4): 1637–42. doi:10.1073/pnas.031586998. PMID 11172003.
Yang J, Kim O, Wu J, Qiu Y (2002). "Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1. A possible role of ETK in regulation of vesicle trafficking.". J. Biol. Chem. 277 (33): 30219–26. doi:10.1074/jbc.M111933200. PMID 11877430.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Fouraux MA, Deneka M, Ivan V, et al. (2004). "Rabip4' is an effector of rab5 and rab4 and regulates transport through early endosomes.". Mol. Biol. Cell 15 (2): 611–24. doi:10.1091/mbc.E03-05-0343. PMID 14617813.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMID 15342556.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.