RPS25

From Wikipedia, the free encyclopedia

Ribosomal protein S25

Identifiers

External IDs

OMIM: 180465 MGI: 1922867 HomoloGene: 68149

Gene ontology
Molecular Function:	• RNA binding • structural constituent of ribosome
Cellular Component:	• cytosolic small ribosomal subunit (sensu Eukaryota) • ribonucleoprotein complex
Biological Process:	• translation

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_001028 (mRNA)
NP_001019 (protein)

NM_024266 (mRNA)
NP_077228 (protein)

Location

Chr 11: 118.39 - 118.39 Mb

n/a

Pubmed search

[1]

[2]

Ribosomal protein S25, also known as RPS25, is a human gene.^[1]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S25E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[1]

[edit] References

^ ^a ^b Entrez Gene: RPS25 ribosomal protein S25.

[edit] Further reading

Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins.". Biochem. Cell Biol. 73 (11-12): 933–47. PMID 8722009.
Li M, Center MS (1992). "Regulation of ribosomal protein S25 in HL60 cells isolated for resistance to adriamycin.". FEBS Lett. 298 (2-3): 142–4. PMID 1544436.
Li ML, Latoud C, Center MS (1992). "Cloning and sequencing a cDNA encoding human ribosomal protein S25.". Gene 107 (2): 329–33. PMID 1748303.
Marion MJ, Marion C (1988). "Ribosomal proteins S2, S6, S10, S14, S15 and S25 are localized on the surface of mammalian 40 S subunits and stabilize their conformation. A study with immobilized trypsin.". FEBS Lett. 232 (2): 281–5. PMID 3378620.
Kato S, Sekine S, Oh SW, et al. (1995). "Construction of a human full-length cDNA bank.". Gene 150 (2): 243–50. PMID 7821789.
Imai T, Sudo K, Miwa T (1994). "Assignment of the human ribosomal protein S25 gene (RPS25) to chromosome 11q23.3 by sequence analysis of the marker D11S456.". Genomics 20 (1): 142–3. doi:10.1006/geno.1994.1145. PMID 8020948.
Miwa T, Sudo K, Nakamura Y, Imai T (1993). "Fifty sequenced-tagged sites on human chromosome 11.". Genomics 17 (1): 211–4. doi:10.1006/geno.1993.1304. PMID 8406452.
Vladimirov SN, Ivanov AV, Karpova GG, et al. (1996). "Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry.". Eur. J. Biochem. 239 (1): 144–9. PMID 8706699.
Kenmochi N, Kawaguchi T, Rozen S, et al. (1998). "A map of 75 human ribosomal protein genes.". Genome Res. 8 (5): 509–23. PMID 9582194.
Kubota S, Copeland TD, Pomerantz RJ (1999). "Nuclear and nucleolar targeting of human ribosomal protein S25: common features shared with HIV-1 regulatory proteins.". Oncogene 18 (7): 1503–14. doi:10.1038/sj.onc.1202429. PMID 10050887.
Ajuh P, Kuster B, Panov K, et al. (2001). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry.". EMBO J. 19 (23): 6569–81. doi:10.1093/emboj/19.23.6569. PMID 11101529.
Yoshihama M, Uechi T, Asakawa S, et al. (2002). "The human ribosomal protein genes: sequencing and comparative analysis of 73 genes.". Genome Res. 12 (3): 379–90. doi:10.1101/gr.214202. PMID 11875025.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMID 15231747.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Yu Y, Ji H, Doudna JA, Leary JA (2005). "Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes.". Protein Sci. 14 (6): 1438–46. doi:10.1110/ps.041293005. PMID 15883184.
Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome.". Cell 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.