RPL9

From Wikipedia, the free encyclopedia

Ribosomal protein L9

PDB rendering based on 2cql.

Available structures: 2cql

Identifiers

Symbol(s)

RPL9; DKFZp313J1510; FLJ27456; MGC15545; NPC-A-16

External IDs

OMIM: 603686 MGI: 1298373 HomoloGene: 68697

Gene ontology
Molecular Function:	• RNA binding • structural constituent of ribosome
Cellular Component:	• intracellular • ribosome
Biological Process:	• translation

Orthologs

Human

Mouse

Refseq

NM_000661 (mRNA)
NP_000652 (protein)

NM_011292 (mRNA)
NP_035422 (protein)

Location

Chr 4: 39.13 - 39.14 Mb

Chr 13: 72.92 - 72.92 Mb

Pubmed search

[1]

[2]

Ribosomal protein L9, also known as RPL9, is a human gene.^[1]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L6P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.^[1]

[edit] References

^ ^a ^b Entrez Gene: RPL9 ribosomal protein L9.

[edit] Further reading

Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins.". Biochem. Cell Biol. 73 (11-12): 933–47. PMID 8722009.
Hori N, Murakawa K, Matoba R, et al. (1993). "A new human ribosomal protein sequence, homologue of rat L9.". Nucleic Acids Res. 21 (18): 4395. PMID 8415001.
Mazuruk K, Schoen TJ, Chader GJ, et al. (1996). "Structural organization and chromosomal localization of the human ribosomal protein L9 gene.". Biochim. Biophys. Acta 1305 (3): 151–62. PMID 8597601.
Kenmochi N, Kawaguchi T, Rozen S, et al. (1998). "A map of 75 human ribosomal protein genes.". Genome Res. 8 (5): 509–23. PMID 9582194.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus.". Curr. Biol. 12 (1): 1–11. PMID 11790298.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics.". Nature 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer.". Mamm. Genome 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674.