RPL31

From Wikipedia, the free encyclopedia

Ribosomal protein L31

Identifiers

RPL31; MGC88191

External IDs

Gene ontology
Molecular Function:	• RNA binding • structural constituent of ribosome
Cellular Component:	• intracellular • ribosome • cytosolic large ribosomal subunit (sensu Eukaryota)
Biological Process:	• translation

Orthologs

Human

Mouse

Entrez

6160

n/a

Refseq

NM_000993 (mRNA)
NP_000984 (protein)

n/a (mRNA)
n/a (protein)

Pubmed search

[1]

n/a

Ribosomal protein L31, also known as RPL31, is a human gene.^[1]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L31E family of ribosomal proteins. It is located in the cytoplasm. Higher levels of expression of this gene in familial adenomatous polyps compared to matched normal tissues have been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[1]

[edit] References

^ ^a ^b Entrez Gene: RPL31 ribosomal protein L31.

[edit] Further reading

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Nobori T, Hexdall LE, Carson DA (1989). "cDNA sequence of human ribosomal protein L31.". Nucleic Acids Res. 17 (17): 7105. PMID 2780320.
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Odintsova TI, Müller EC, Ivanov AV, et al. (2004). "Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing.". J. Protein Chem. 22 (3): 249–58. PMID 12962325.
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Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.