RPL27

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Ribosomal protein L27
Identifiers
Symbol(s) RPL27;
External IDs OMIM: 607526 HomoloGene: 765
Orthologs
Human Mouse
Entrez 6155 n/a
Ensembl ENSG00000131469 n/a
Uniprot P61353 n/a
Refseq NM_000988 (mRNA)
NP_000979 (protein)		 n/a (mRNA)
n/a (protein)
Location Chr 17: 38.4 - 38.41 Mb n/a
Pubmed search [1] n/a

Ribosomal protein L27, also known as RPL27, is a human gene.[1]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L27E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[1]

[edit] References

  1. ^ a b Entrez Gene: RPL27 ribosomal protein L27.

[edit] Further reading

  • Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins.". Biochem. Cell Biol. 73 (11-12): 933–47. PMID 8722009. 
  • Jones KW, Chevrette M, Shapero MH, Fournier RE (1993). "Generation of region- and species-specific expressed gene probes from somatic cell hybrids.". Nat. Genet. 1 (4): 278–83. doi:10.1038/ng0792-278. PMID 1302024. 
  • Miki Y, Swensen J, Shattuck-Eidens D, et al. (1994). "A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.". Science 266 (5182): 66–71. PMID 7545954. 
  • Harshman K, Bell R, Rosenthal J, et al. (1995). "Comparison of the positional cloning methods used to isolate the BRCA1 gene.". Hum. Mol. Genet. 4 (8): 1259–66. PMID 7581362. 
  • Gallagher RA, McClean PM, Malik AN (1994). "Cloning and nucleotide sequence of a full length cDNA encoding ribosomal protein L27 from human fetal kidney.". Biochim. Biophys. Acta 1217 (3): 329–32. PMID 8148381. 
  • Uechi T, Tanaka T, Kenmochi N (2001). "A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders.". Genomics 72 (3): 223–30. doi:10.1006/geno.2000.6470. PMID 11401437. 
  • Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus.". Curr. Biol. 12 (1): 1–11. PMID 11790298. 
  • Yoshihama M, Uechi T, Asakawa S, et al. (2002). "The human ribosomal protein genes: sequencing and comparative analysis of 73 genes.". Genome Res. 12 (3): 379–90. doi:10.1101/gr.214202. PMID 11875025. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics.". Nature 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413. 
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