RPA4

From Wikipedia, the free encyclopedia

Replication protein A4, 34kDa

Identifiers

RPA4; HSU24186; MGC120333; MGC120334

External IDs

Gene ontology
Molecular Function:	• nucleic acid binding • single-stranded DNA binding
Cellular Component:	• nucleus • DNA replication factor A complex
Biological Process:	• DNA replication • DNA replication initiation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

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Refseq

NM_013347 (mRNA)
NP_037479 (protein)

n/a (mRNA)
n/a (protein)

Location

Chr X: 96.03 - 96.03 Mb

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Pubmed search

[1]

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Replication protein A4, 34kDa, also known as RPA4, is a human gene.^[1]

[edit] References

^ Entrez Gene: RPA4 replication protein A4, 34kDa.

[edit] Further reading

Wu X, Yang Z, Liu Y, Zou Y (2006). "Preferential localization of hyperphosphorylated replication protein A to double-strand break repair and checkpoint complexes upon DNA damage.". Biochem. J. 391 (Pt 3): 473–80. doi:10.1042/BJ20050379. PMID 15929725.
Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome.". Nature 434 (7031): 325–37. doi:10.1038/nature03440. PMID 15772651.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Parker A, Gu Y, Mahoney W, et al. (2001). "Human homolog of the MutY repair protein (hMYH) physically interacts with proteins involved in long patch DNA base excision repair.". J. Biol. Chem. 276 (8): 5547–55. doi:10.1074/jbc.M008463200. PMID 11092888.
Amacker M, Hottiger M, Mossi R, Hübscher U (1997). "HIV-1 nucleocapsid protein and replication protein A influence the strand displacement DNA synthesis of lentiviral reverse transcriptase.". AIDS 11 (4): 534–6. PMID 9084803.
Keshav KF, Chen C, Dutta A (1995). "Rpa4, a homolog of the 34-kilodalton subunit of the replication protein A complex.". Mol. Cell. Biol. 15 (6): 3119–28. PMID 7760808.
Li L, Lu X, Peterson CA, Legerski RJ (1995). "An interaction between the DNA repair factor XPA and replication protein A appears essential for nucleotide excision repair.". Mol. Cell. Biol. 15 (10): 5396–402. PMID 7565690.