RPA3

From Wikipedia, the free encyclopedia

Replication protein A3, 14kDa

PDB rendering based on 1l1o.

Available structures: 1l1o, 1quq

Identifiers

Symbol(s)

RPA3; REPA3

External IDs

OMIM: 179837 MGI: 1915490 HomoloGene: 68285

Gene ontology
Molecular Function:	• single-stranded DNA binding
Cellular Component:	• nucleus • DNA replication factor A complex
Biological Process:	• DNA replication • DNA repair

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_002947 (mRNA)
NP_002938 (protein)

NM_026632 (mRNA)
NP_080908 (protein)

Location

Chr 7: 7.64 - 7.72 Mb

Chr 6: 8.21 - 8.21 Mb

Pubmed search

[1]

[2]

Replication protein A3, 14kDa, also known as RPA3, is a human gene.^[1]

[edit] References

^ Entrez Gene: RPA3 replication protein A3, 14kDa.

[edit] Further reading

Iftode C, Daniely Y, Borowiec JA (1999). "Replication protein A (RPA): the eukaryotic SSB.". Crit. Rev. Biochem. Mol. Biol. 34 (3): 141-80. PMID 10473346.
Keshav KF, Chen C, Dutta A (1995). "Rpa4, a homolog of the 34-kilodalton subunit of the replication protein A complex.". Mol. Cell. Biol. 15 (6): 3119-28. PMID 7760808.
Umbricht CB, Griffin CA, Hawkins AL, et al. (1994). "High-resolution genomic mapping of the three human replication protein A genes (RPA1, RPA2, and RPA3).". Genomics 20 (2): 249-57. doi:10.1006/geno.1994.1161. PMID 8020972.
Umbricht CB, Erdile LF, Jabs EW, Kelly TJ (1993). "Cloning, overexpression, and genomic mapping of the 14-kDa subunit of human replication protein A.". J. Biol. Chem. 268 (9): 6131-8. PMID 8454588.
Amacker M, Hottiger M, Mossi R, Hübscher U (1997). "HIV-1 nucleocapsid protein and replication protein A influence the strand displacement DNA synthesis of lentiviral reverse transcriptase.". AIDS 11 (4): 534-6. PMID 9084803.
Bochkareva E, Frappier L, Edwards AM, Bochkarev A (1998). "The RPA32 subunit of human replication protein A contains a single-stranded DNA-binding domain.". J. Biol. Chem. 273 (7): 3932-6. PMID 9461578.
"Toward a complete human genome sequence." (1999). Genome Res. 8 (11): 1097-108. PMID 9847074.
Mer G, Bochkarev A, Gupta R, et al. (2000). "Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA.". Cell 103 (3): 449-56. PMID 11081631.
Habel JE, Ohren JF, Borgstahl GE (2001). "Dynamic light-scattering analysis of full-length human RPA14/32 dimer: purification, crystallization and self-association.". Acta Crystallogr. D Biol. Crystallogr. 57 (Pt 2): 254-9. PMID 11173472.
Bochkareva E, Korolev S, Lees-Miller SP, Bochkarev A (2002). "Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA.". EMBO J. 21 (7): 1855-63. doi:10.1093/emboj/21.7.1855. PMID 11927569.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Kneissl M, Pütter V, Szalay AA, Grummt F (2003). "Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells.". J. Mol. Biol. 327 (1): 111-28. PMID 12614612.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767-72. doi:10.1126/science.1083423. PMID 12690205.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157-64. doi:10.1038/nature01782. PMID 12853948.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.