Rotor syndrome
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Rotor syndrome Classification and external resources |
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Bilirubin | |
ICD-10 | E80.6 |
ICD-9 | 277.4 |
OMIM | 237450 |
DiseasesDB | 11671 |
MeSH | D006933 |
Rotor syndrome is a rare, relatively benign autosomal recessive bilirubin disorder of unknown origin.
Contents |
[edit] Presentation
It has many things in common with Dubin-Johnson syndrome except that in Rotor Syndrome, the liver cells are not pigmented. The main symptom is a non-itching jaundice. There is a rise in bilirubin in the patient's serum, mainly of the conjugated type.
It can be differentiated from Dubin-Johnson syndrome in the following ways:
Rotor syndrome | DJS | |
appearance of liver | normal histology and appearance | liver has black pigmentation |
gallbladder visualization | gallbladder can be visualized by USG | gallbladder cannot be visualized |
total urine coproporphyrin content | high with <70% being isomer 1 | normal with >80% being isomer 1 (normal urine contains more of isomer 3 than isomer 1) |
[edit] Eponym
Rotor syndrome is named after the Filipino internist, Arturo Belleza Rotor (1907-1988).[1]
[edit] See also
[edit] References
[edit] External links
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