Rosenmund reduction

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The Rosenmund reduction is a chemical reaction that reduces an acid halide to an aldehyde using hydrogen gas over palladium-on-carbon poisoned with barium sulfate.[1][2][3] The reaction was named after Karl Wilhelm Rosenmund.

The Rosenmund reduction

The catalyst must be poisoned because otherwise the catalyst is too active and will reduce the acid chloride to a primary alcohol.

Diisobutylaluminium hydride (DIBALH) can also reduce acid chlorides to aldehydes.

[edit] See also

[edit] References

  1. ^ Rosenmund, K. W. (1918). "Über eine neue Methode zur Darstellung von Aldehyden. 1. Mitteilung". Chemische Berichte 51: 585–593. doi:10.1002/cber.19180510170. 
  2. ^ Rosenmund, K. W., Zetzsche, F. (1921). "Über die Beeinflussung der Wirksamkeit von Katalysatoren, 1. bis 5.". Chemische Berichte 54: 425–437; 638–647; 1092–1098; 2033–2037; 2038–2042. 
  3. ^ Mosettig, E.; Mozingo, R. Org. React. 1948, 4, 362. (Review)

[edit] Further reading