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| RNA-OUT |
 |
| Type: |
Gene; |
| 2° structure: |
Predicted; Pfold |
| Seed alignment: |
PubMed |
| Avg length: |
70.0 nucleotides |
| Avg identity: |
96% |
|
RNA-OUT is a non-coding RNA that is antisense to the RNA-IN non-coding RNA. Transposition of insertion sequence IS10 is regulated by an anti-sense RNA which inhibits transposase expression when IS10 is present in multiple copies per cell. RNA-OUT consists of a stem-loop domain topped by a flexibly paired loop; the 5' end of the target molecule, RNA-IN, is complementary to the top of the loop, and complementarity extends for 35 nucleotides down one side of RNA-OUT.[1]
[edit] References
- ^ Kittle, JD; Simons RW, Lee J, Kleckner N (1989). "Insertion sequence IS10 anti-sense pairing initiates by an interaction between the 5' end of the target RNA and a loop in the anti-sense RNA". J Mol Biol 210: 561–572. doi:10.1016/0022-2836(89)90132-0. PMID 2482367.
[edit] External links
