Administrative areas: Scottish Borders, Scotland · Northumberland, England Flows into: North Sea Towns (upstream to downstream): Peebles · Galashiels · Melrose · Newstead · St. Boswells · Kelso · Coldstream · Berwick-upon-Tweed
Major tributaries (upstream to downstream by confluence): Cor Water · Talla Water · Holms Water · Lyne Water · Manor Water Quair Water · Leithen Water · Caddon Water · River Ettrick · Gala Water · River Leader · River Teviot · River Till · Whiteadder Water
Major bridges (upstream to downstream): Leaderfoot Viaduct · Dryburgh Bridge · Mertoun Bridge · Rennie Bridge Hunter Bridge · Coldstream Bridge · Ladykirk and Norham Bridge · Union Bridge · A1 bridge, River Tweed Royal Border Bridge · Royal Tweed Bridge · Berwick Bridge