RIT1
From Wikipedia, the free encyclopedia
Ras-like without CAAX 1
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Identifiers | ||||||||||||||
Symbol(s) | RIT1; MGC125864; MGC125865; RIBB; RIT; ROC1 | |||||||||||||
External IDs | OMIM: 609591 MGI: 108053 HomoloGene: 56003 | |||||||||||||
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RNA expression pattern | ||||||||||||||
Orthologs | ||||||||||||||
Human | Mouse | |||||||||||||
Entrez | 6016 | 19769 | ||||||||||||
Ensembl | ENSG00000143622 | ENSMUSG00000028057 | ||||||||||||
Uniprot | Q92963 | P70426 | ||||||||||||
Refseq | NM_006912 (mRNA) NP_008843 (protein) |
NM_009069 (mRNA) NP_033095 (protein) |
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Location | Chr 1: 154.13 - 154.15 Mb | Chr 3: 88.8 - 88.82 Mb | ||||||||||||
Pubmed search | [1] | [2] |
Ras-like without CAAX 1, also known as RIT1, is a human gene.[1]
RIT belongs to the RAS (HRAS; MIM 190020) subfamily of small GTPases (Hynds et al., 2003).[supplied by OMIM][1]
[edit] References
[edit] Further reading
- Lee CH, Della NG, Chew CE, Zack DJ (1996). "Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins.". J. Neurosci. 16 (21): 6784–94. PMID 8824319.
- Wes PD, Yu M, Montell C (1997). "RIC, a calmodulin-binding Ras-like GTPase.". EMBO J. 15 (21): 5839–48. PMID 8918462.
- Shao H, Kadono-Okuda K, Finlin BS, Andres DA (1999). "Biochemical characterization of the Ras-related GTPases Rit and Rin.". Arch. Biochem. Biophys. 371 (2): 207–19. doi: . PMID 10545207.
- Shao H, Andres DA (2000). "A novel RalGEF-like protein, RGL3, as a candidate effector for rit and Ras.". J. Biol. Chem. 275 (35): 26914–24. doi: . PMID 10869344.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi: . PMID 12477932.
- Hynds DL, Spencer ML, Andres DA, Snow DM (2004). "Rit promotes MEK-independent neurite branching in human neuroblastoma cells.". J. Cell. Sci. 116 (Pt 10): 1925–35. doi: . PMID 12668729.
- Li JT, Liu W, Kuang ZH, et al. (2004). "[Mutation and amplification of RIT1 gene in hepatocellular carcinoma]". Zhonghua Yi Xue Yi Chuan Xue Za Zhi 21 (1): 43–6. PMID 14767908.
- Shi GX, Andres DA (2005). "Rit contributes to nerve growth factor-induced neuronal differentiation via activation of B-Raf-extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades.". Mol. Cell. Biol. 25 (2): 830–46. doi: . PMID 15632082.
- Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells.". Science 307 (5715): 1621–5. doi: . PMID 15761153.
- Benmaamar R, Pagano M (2006). "Involvement of the SCF complex in the control of Cdh1 degradation in S-phase.". Cell Cycle 4 (9): 1230–2. PMID 16123585.