RINT1

From Wikipedia, the free encyclopedia

RAD50 interactor 1

Identifiers

RINT1; DKFZp667H2324; RINT-1

External IDs

OMIM: 610089 MGI: 1916233 HomoloGene: 11070

Gene ontology
Molecular Function:	• protein binding
Cellular Component:	• endoplasmic reticulum • membrane
Biological Process:	• ER to Golgi vesicle-mediated transport • cell cycle • protein transport • G2/M transition DNA damage checkpoint

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_021930 (mRNA)
NP_068749 (protein)

NM_177323 (mRNA)
NP_796297 (protein)

Location

Chr 7: 104.96 - 105 Mb

Chr 5: 23.3 - 23.33 Mb

Pubmed search

[1]

[2]

RAD50 interactor 1, also known as RINT1, is a human gene.^[1]

[edit] References

^ Entrez Gene: RINT1 RAD50 interactor 1.

[edit] Further reading

"Toward a complete human genome sequence." (1999). Genome Res. 8 (11): 1097-108. PMID 9847074.
Xiao J, Liu CC, Chen PL, Lee WH (2001). "RINT-1, a novel Rad50-interacting protein, participates in radiation-induced G(2)/M checkpoint control.". J. Biol. Chem. 276 (9): 6105-11. doi:10.1074/jbc.M008893200. PMID 11096100.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157-64. doi:10.1038/nature01782. PMID 12853948.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Hirose H, Arasaki K, Dohmae N, et al. (2005). "Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi.". EMBO J. 23 (6): 1267-78. doi:10.1038/sj.emboj.7600135. PMID 15029241.
Nakajima K, Hirose H, Taniguchi M, et al. (2005). "Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion.". EMBO J. 23 (16): 3216-26. doi:10.1038/sj.emboj.7600333. PMID 15272311.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Arasaki K, Taniguchi M, Tani K, Tagaya M (2006). "RINT-1 regulates the localization and entry of ZW10 to the syntaxin 18 complex.". Mol. Biol. Cell 17 (6): 2780-8. doi:10.1091/mbc.E05-10-0973. PMID 16571679.
Kong LJ, Meloni AR, Nevins JR (2006). "The Rb-related p130 protein controls telomere lengthening through an interaction with a Rad50-interacting protein, RINT-1.". Mol. Cell 22 (1): 63-71. doi:10.1016/j.molcel.2006.02.016. PMID 16600870.
Lin X, Liu CC, Gao Q, et al. (2007). "RINT-1 serves as a tumor suppressor and maintains Golgi dynamics and centrosome integrity for cell survival.". Mol. Cell. Biol. 27 (13): 4905-16. doi:10.1128/MCB.02396-06. PMID 17470549.
Sun Y, Shestakova A, Hunt L, et al. (2007). "Rab6 regulates both ZW10/RINT-1 and conserved oligomeric Golgi complex-dependent Golgi trafficking and homeostasis.". Mol. Biol. Cell 18 (10): 4129-42. doi:10.1091/mbc.E07-01-0080. PMID 17699596.