Ricinine nitrilase

From Wikipedia, the free encyclopedia

In enzymology, a ricinine nitrilase (EC 3.5.5.2) is an enzyme that catalyzes the chemical reaction

ricinine + 2 H₂O 3-carboxy-4-methoxy-N-methyl-2-pyridone + NH₃

Thus, the two substrates of this enzyme are ricinine and H₂O, whereas its two products are 3-carboxy-4-methoxy-N-methyl-2-pyridone and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in nitriles. The systematic name of this enzyme class is ricinine aminohydrolase. This enzyme participates in nitrogen metabolism.

[edit] References

• IUBMB entry for 3.5.5.2
• BRENDA references for 3.5.5.2 (Recommended.)
• PubMed references for 3.5.5.2
• PubMed Central references for 3.5.5.2
• Google Scholar references for 3.5.5.2
• ROBINSON WG, HOOK RH (1964). "RICININE NITRILASE. I. REACTION PRODUCT AND SUBSTRATE SPECIFICITY". J. Biol. Chem. 239: 4257–62. PMID 14247679. 
• HOOK RH, ROBINSON WG (1964). "RICININE NITRILASE. II. PURIFICATION AND PROPERTIES". J. Biol. Chem. 239: 4263–7. PMID 14247680. 
• Pace HC, Brenner C (2001). "The nitrilase superfamily: classification, structure and function". Genome. Biol. 2: REVIEWS0001. PMID 11380987. 

[edit] External links

The CAS registry number for this enzyme class is 9075-40-5.

• IUBMB entry for 3.5.5.2

• KEGG entry for 3.5.5.2

• BRENDA entry for 3.5.5.2

• NiceZyme view of 3.5.5.2

• EC2PDB: PDB structures for 3.5.5.2

• PRIAM entry for 3.5.5.2

• PUMA2 entry for 3.5.5.2

• IntEnz: Integrated Enzyme entry for 3.5.5.2

• MetaCyc entry for 3.5.5.2

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047426: ricinine nitrilase

• AMIGO entry for GO code 0047426: ricinine nitrilase