RIC8A

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Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
Identifiers
Symbol(s) RIC8A; RIC8; MGC104517; MGC131931; MGC148073; MGC148074; synembryn
External IDs OMIM: 609146 MGI: 2141866 HomoloGene: 23331
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 60626 101489
Ensembl ENSG00000177963 ENSMUSG00000025485
Uniprot Q9NPQ8 Q3TIR3
Refseq NM_021932 (mRNA)
NP_068751 (protein)		 NM_053194 (mRNA)
NP_444424 (protein)
Location Chr 11: 0.2 - 0.21 Mb Chr 7: 140.71 - 140.72 Mb
Pubmed search [1] [2]

Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans), also known as RIC8A, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: RIC8A resistance to inhibitors of cholinesterase 8 homolog A (C. elegans).

[edit] Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Miller KG, Emerson MD, McManus JR, Rand JB (2000). "RIC-8 (Synembryn): a novel conserved protein that is required for G(q)alpha signaling in the C. elegans nervous system.". Neuron 27 (2): 289–99. PMID 10985349. 
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863. 
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Tall GG, Krumins AM, Gilman AG (2003). "Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor.". J. Biol. Chem. 278 (10): 8356–62. doi:10.1074/jbc.M211862200. PMID 12509430. 
  • Klattenhoff C, Montecino M, Soto X, et al. (2003). "Human brain synembryn interacts with Gsalpha and Gqalpha and is translocated to the plasma membrane in response to isoproterenol and carbachol.". J. Cell. Physiol. 195 (2): 151–7. doi:10.1002/jcp.10300. PMID 12652642. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901. 
  • Nishimura A, Okamoto M, Sugawara Y, et al. (2006). "Ric-8A potentiates Gq-mediated signal transduction by acting downstream of G protein-coupled receptor in intact cells.". Genes Cells 11 (5): 487–98. doi:10.1111/j.1365-2443.2006.00959.x. PMID 16629901. 
  • Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. 
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