Ribokinase

From Wikipedia, the free encyclopedia

In enzymology, a ribokinase (EC 2.7.1.15) is an enzyme that catalyzes the chemical reaction

ATP + D-ribose ADP + D-ribose 5-phosphate

Thus, the two substrates of this enzyme are ATP and D-ribose, whereas its two products are ADP and D-ribose 5-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-ribose 5-phosphotransferase. Other names in common use include deoxyribokinase, ribokinase (phosphorylating), and D-ribokinase. This enzyme participates in pentose phosphate pathway.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1GQT, 1RK2, 1RKA, 1RKD, 1RKS, 1VM7, and 2FV7.

[edit] References

• IUBMB entry for 2.7.1.15
• BRENDA references for 2.7.1.15 (Recommended.)
• PubMed references for 2.7.1.15
• PubMed Central references for 2.7.1.15
• Google Scholar references for 2.7.1.15
• Agranoff BW and Brady RO (1956). "Purification and properties of calf liver ribokinase". J. Biol.Chem. 219: 221–229. 
• GINSBURG A (1959). "A deoxyribokinase from Lactobacillus plantarum". J. Biol. Chem. 234: 481–7. PMID 13641245. 

[edit] External links

The CAS registry number for this enzyme class is 9026-84-0.

• IUBMB entry for 2.7.1.15

• KEGG entry for 2.7.1.15

• BRENDA entry for 2.7.1.15

• NiceZyme view of 2.7.1.15

• EC2PDB: PDB structures for 2.7.1.15

• PRIAM entry for 2.7.1.15

• PUMA2 entry for 2.7.1.15

• IntEnz: Integrated Enzyme entry for 2.7.1.15

• MetaCyc entry for 2.7.1.15

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0004747: ribokinase

• AMIGO entry for GO code 0004747: ribokinase