RHOT1

From Wikipedia, the free encyclopedia

Ras homolog gene family, member T1

Identifiers

RHOT1; ARHT1; FLJ11040; FLJ12633; MIRO-1

External IDs

MGI: 1926078 HomoloGene: 56803

Gene ontology
Molecular Function:	• nucleotide binding • molecular_function • calcium ion binding • GTP binding • hydrolase activity
Cellular Component:	• intracellular • mitochondrion • membrane • integral to membrane • outer membrane • integral to mitochondrial outer membrane
Biological Process:	• apoptosis • small GTPase mediated signal transduction • cell homeostasis • mitochondrion transport along microtubule

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_001033566 (mRNA)
NP_001028738 (protein)

NM_021536 (mRNA)
NP_067511 (protein)

Location

Chr 17: 27.49 - 27.58 Mb

Chr 11: 80.03 - 80.08 Mb

Pubmed search

[1]

[2]

Ras homolog gene family, member T1, also known as RHOT1, is a human gene.^[1]

[edit] References

^ Entrez Gene: RHOT1 ras homolog gene family, member T1.

[edit] Further reading

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788-95. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422-35. doi:10.1101/gr.154701. PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Fransson A, Ruusala A, Aspenström P (2003). "Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis.". J. Biol. Chem. 278 (8): 6495-502. doi:10.1074/jbc.M208609200. PMID 12482879.
Aspenström P, Fransson A, Saras J (2004). "Rho GTPases have diverse effects on the organization of the actin filament system.". Biochem. J. 377 (Pt 2): 327-37. doi:10.1042/BJ20031041. PMID 14521508.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707-16. doi:10.1038/nbt971. PMID 15146197.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136-44. doi:10.1101/gr.2576704. PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415-8. doi:10.1093/nar/gkj139. PMID 16381901.
Fransson S, Ruusala A, Aspenström P (2006). "The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking.". Biochem. Biophys. Res. Commun. 344 (2): 500-10. doi:10.1016/j.bbrc.2006.03.163. PMID 16630562.