Rhamnulose-1-phosphate aldolase

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In enzymology, a rhamnulose-1-phosphate aldolase (EC 4.1.2.19) is an enzyme that catalyzes the chemical reaction

L-rhamnulose 1-phosphate \rightleftharpoons glycerone phosphate + (S)-lactaldehyde

Hence, this enzyme has one substrate, L-rhamnulose 1-phosphate, and two products, glycerone phosphate and (S)-lactaldehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is L-rhamnulose-1-phosphate (S)-lactaldehyde-lyase (glycerone-phosphate-forming). Other names in common use include rhamnulose phosphate aldolase, L-rhamnulose 1-phosphate aldolase, L-rhamnulose-phosphate aldolase, and L-rhamnulose-1-phosphate lactaldehyde-lyase. This enzyme participates in pentose and glucuronate interconversions and fructose and mannose metabolism.

Contents

[edit] Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1GT7 and 1OJR.

[edit] References

[edit] External links

The CAS registry number for this enzyme class is 9054-58-4.

[edit] Gene Ontology (GO) codes