Retinal oxidase

From Wikipedia, the free encyclopedia

In enzymology, a retinal oxidase (EC 1.2.3.11) is an enzyme that catalyzes the chemical reaction

retinal + O₂ + H₂O retinoate + H₂O₂

The 3 substrates of this enzyme are retinal, O₂, and H₂O, whereas its two products are retinoate and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with oxygen as acceptor. The systematic name of this enzyme class is retinal:oxygen oxidoreductase. This enzyme is also called retinene oxidase. This enzyme participates in retinol metabolism.

[edit] References

• IUBMB entry for 1.2.3.11
• BRENDA references for 1.2.3.11 (Recommended.)
• PubMed references for 1.2.3.11
• PubMed Central references for 1.2.3.11
• Google Scholar references for 1.2.3.11
• Mandal SK, Datta Chaudhuri B (1987). "Enzymic oxidation of vitamin A aldehyde to vitamin A acid by rat livers of experimental thyroid disorders". Indian. J. Exp. Biol. 25: 796–7. PMID 3452601. 
• Huang DY, Furukawa A, Ichikawa Y (1999). "Molecular cloning of retinal oxidase/aldehyde oxidase cDNAs from rabbit and mouse livers and functional expression of recombinant mouse retinal oxidase cDNA in Escherichia coli". Arch. Biochem. Biophys. 364: 264–72. doi:10.1006/abbi.1999.1129. PMID 10190983. 

[edit] External links

The CAS registry number for this enzyme class is 9033-52-7.

• IUBMB entry for 1.2.3.11

• KEGG entry for 1.2.3.11

• BRENDA entry for 1.2.3.11

• NiceZyme view of 1.2.3.11

• EC2PDB: PDB structures for 1.2.3.11

• PRIAM entry for 1.2.3.11

• PUMA2 entry for 1.2.3.11

• IntEnz: Integrated Enzyme entry for 1.2.3.11

• MetaCyc entry for 1.2.3.11

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050250: retinal oxidase

• AMIGO entry for GO code 0050250: retinal oxidase