Retinal isomerase

From Wikipedia, the free encyclopedia

In enzymology, a retinal isomerase (EC 5.2.1.3) is an enzyme that catalyzes the chemical reaction

all-trans-retinal 11-cis-retinal

Hence, this enzyme has one substrate, all-trans-retinal, and one product, 11-cis-retinal.

This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is all-trans-retinal 11-cis-trans-isomerase. Other names in common use include retinene isomerase, and retinoid isomerase. This enzyme participates in retinol metabolism.

[edit] References

• IUBMB entry for 5.2.1.3
• BRENDA references for 5.2.1.3 (Recommended.)
• PubMed references for 5.2.1.3
• PubMed Central references for 5.2.1.3
• Google Scholar references for 5.2.1.3
• HUBBARD R (1956). "Retinene isomerase". J. Gen. Physiol. 39: 935–62. doi:10.1085/jgp.39.6.935. PMID 13346046. 
• Shichi H, Somers RL (1974). "Possible involvement of retinylidene phospholipid in photoisomerization of all-trans-retinal to 11-cis-retinal". J. Biol. Chem. 249: 6570–7. PMID 4472816. 

[edit] External links

The CAS registry number for this enzyme class is 9023-76-1.

• IUBMB entry for 5.2.1.3

• KEGG entry for 5.2.1.3

• BRENDA entry for 5.2.1.3

• NiceZyme view of 5.2.1.3

• EC2PDB: PDB structures for 5.2.1.3

• PRIAM entry for 5.2.1.3

• PUMA2 entry for 5.2.1.3

• IntEnz: Integrated Enzyme entry for 5.2.1.3

• MetaCyc entry for 5.2.1.3

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0004744: retinal isomerase

• AMIGO entry for GO code 0004744: retinal isomerase