Reinke's edema

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Reinke's edema Classification and external resources
ICD-10	J38.4
ICD-9	478.6
DiseasesDB	32572

Reinke's edema, also known as polypoid degeneration, is the swelling of the vocal folds due to fluid collection (edema).

Contents 1 Presentation 2 Causes 3 Histology 4 Treatment 5 Eponym 6 See also 7 References 8 External links

[edit] Presentation

Reinke's edema causes the vocal folds to bilaterally swell giving them an uneven, sac-like appearance. Individuals with Reinke's Edema typically have low-pitched, husky voices.

[edit] Causes

Common causes of Reinke's edema include smoking, gastroesophageal reflux, hormonal changes such as hypothyroidism and chronic voice abuse.

[edit] Histology

Histopathology: biopsy of the vocal cord may be used to help in diagnosis in some cases. Histology shows oedema in the stroma.

[edit] Treatment

The first course of treatment is to remove the source of the irritant (e.g. smoking cessation, vocal rest, etc.). This can be effective if done soon after development of the edema. Surgery is also an option and can result in some restoration of the voice but is ineffective in complete restoration of the voice to its original state.

[edit] Eponym

It is named for Friedrich Reinke.^[1][2]

[edit] See also

• List of voice disorders

[edit] References

1. ^ synd/2653 at Who Named It
2. ^ F. B. Reinke. Untersuchungen über das menschliche Stimmband. Fortschritte der Medizin, München, 1895, 13: 469-478.

• Benign Vocal Lesions - Nodules, Polyps, Cysts. The Center for Voice at Northwestern University. Retrieved on July 24, 2007.

[edit] External links

• Illustration of Reinke's Edema. The Center for Voice at Northwestern University. Retrieved on July 24, 2007.